Teresa Santos (in collaboration with Ilana Polistchuck, MD) May 16, 2023 Psychotherapy is one of the two main treatments for posttraumatic stress disorder (PTSD). The other is pharmacologic therapy, and selective serotonin reuptake inhibitors (SSRIs) are the first-line treatment. With this approach, however, response rates rarely exceed 60%, and fewer than 20% to 30% of patients achieve full remission. But...
Month: <span>June 2023</span>
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Study: External factors shape genetic predisposition to lipids, Alzheimer’s and heart disease in MLXIPL gene
by Impact Journals LLC Univariate associations of minor alleles of four SNPs from the MLXIPL gene with AD and CHD in two samples drawn from US cohorts (A) and UK biobank (B). Credit: Aging (2023). DOI: 10.18632/aging.204665 A new research paper titled “Exogenous exposures shape genetic predisposition to lipids, Alzheimer’s, and coronary heart disease in the MLXIPL...
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Study shows dementia risk increases the earlier a person develops diabetes
by Diabetologia Credit: CC0 Public Domain New research published in Diabetologia shows an association between type 2 diabetes (T2D) and developing dementia in later life—with the risk of dementia increasing the earlier a person develops T2D. The study is by Ph.D. student Jiaqi Hu and Professor Elizabeth Selvin of the Johns Hopkins Bloomberg School of Public Health, Baltimore,...
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Case study reveals potentially lethal side effects of lecanemab for treatment of Alzheimer’s disease
IOS PRESS IMAGE: THE MOST STRIKING FINDINGS WERE THE MONONUCLEAR ATTACK ON CEREBRAL AMYLOID ANGIOPATHY (HISTIOCYTIC VASCULITIS) WITH FIBRINOID NECROSIS (LEFT, AΒ IMMUNOHISTOCHEMISTRY [4G8]), AND FOCALLY PRONOUNCED AΒ PLAQUE PHAGOCYTOSIS (RIGHT, CD163 IMMUNOHISTOCHEMISTRY), THE COMBINATION OF WHICH DOES NOT OTHERWISE EXIST IN NATURE. CREDIT: JOURNAL OF ALZHEIMER’S DISEASE. Amsterdam, May 24, 2023 – In a noteworthy case...
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Study finds common complication of pacemakers four times higher than previously thought
by Jacqueline Mitchell, Beth Israel Deaconess Medical Center Credit: Journal of the American College of Cardiology (2023). DOI: 10.1016/j.jacc.2023.04.017 About 3 million Americans live with cardiovascular implantable electronic devices—commonly known as pacemakers. These small electronic devices implanted in the chest or abdomen are typically used to treat slow or irregular heart rhythms and they can significantly improve patients’ quality of...
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Existing drugs point to first treatment for strokes linked to dementia
by University of Edinburgh Micrograph showing cortical pseudolaminar necrosis, a finding seen in strokes on medical imaging and at autopsy. H&E-LFB stain. Credit: Nephron/Wikipedia People who experience a type of stroke linked with nearly half of all dementias could be treated for the first time by repurposing two cheap and common drugs, a trial shows. Researchers found that...
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Five rare and unusual psychiatric syndromes—including one where people believe they are dead
by Mark Griffiths, The Conversation Credit: Pixabay/CC0 Public Domain Most people are familiar with psychiatric disorders such as schizophrenia and bipolar disorder, but some conditions are so rare that many psychiatrists won’t come across a single case in their professional lives. Here I present five of the rarest—and strangest—syndromes known to psychiatry. 1. Fregoli syndrome Fregoli syndrome is...
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Anesthesia can cause disturbing sexual hallucinations, leading to lasting psychological trauma
by Melody White and C. Michael White, The Conversation Credit: Pixabay/CC0 Public Domain Some patients can have vivid and detailed sexual hallucinations during anesthesia with sedative-hypnotic drugs like propofol, midazolam, diazepam and nitrous oxide. Some make suggestive or sexual comments or act out, such as grabbing or kissing medical professionals or touching themselves in a sexual way. Others awaken erroneously...
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Study finds daily multivitamin supplements improve memory and slow cognitive aging in older adults
by Brigham and Women’s Hospital Credit: Pixabay/CC0 Public Domain Few effective strategies have been shown in randomized clinical trials to improve memory or slow cognitive decline among older adults. Nutritional interventions may play an important role because the brain requires several nutrients for optimal health, and deficiencies in one or more of these nutrients may accelerate cognitive decline....
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New nasal spray to reverse fentanyl and other opioid overdoses gets FDA approval
MATTHEW PERRONE Mon, May 22, 2023 at 2:20 PM MST WASHINGTON (AP) — U.S. health regulators on Monday approved a new easy-to-use version of a medication to reverse overdoses caused by fentanyl and other opioids driving the nation’s drug crisis. Opvee is similar to naloxone, the life-saving drug that has been used for decades to quickly counter overdoses of heroin,...