by Kyoto University Caption: Brain chemical dopamine enables adaptive reward pursuit to overcome lack of reward and ultimately obtain more rewards. Credit: KyotoU/Hiroko Uchida Dopamine has been known to increase when results are promising and decrease when expectations are not met. However, this role does not explain the ability to overcome disappointment. Now, researchers at Kyoto...
Jim Kling June 22, 2023 AUSTIN, TEX. – A new machine-learning analysis of a large group of migraine patients has identified subgroups that share both clinical and therapeutic response traits. The findings could point to new therapeutic strategies, according to study author Ali Ezzati, MD. “A lot of diagnostic criteria that we have in the migraine world come from...
by Columbia University Irving Medical Center Cross-ancestry GWAS for IgAN. Credit: Nature Genetics (2023). DOI: 10.1038/s41588-023-01422-x The cause of a common kidney disease likely lies outside the kidney, according to a new study led by Columbia University researchers. The study, which uncovered 16 new locations in the genome linked to immunoglobulin A (IgA) nephropathy, confirms an earlier hypothesis that...
By Paul McClure June 22, 2023 A new study has found a causal link between napping and brain volume, an indicator of brain healthDepositphotos Napping. Some people do it, and some people don’t. A new study has found that those who are genetically predisposed to taking regular daytime naps may have larger, healthier brains as...
Receptor patterns define key organisational principles in the brain, scientists have discovered. An international team of researchers, studying macaque brains, have mapped out neurotransmitter receptors, revealing a potential role in distinguishing internal thoughts and emotions from those generated by external influences. The comprehensive dataset has been made publicly available, bridging different scales of neuroscience – from the...
Credit: Pixabay/CC0 Public Domain The number of people suffering from diabetes worldwide will more than double to 1.3 billion by 2050 driven by structural racism and gaping inequality between countries, new research predicted on Friday. Every country on the globe will see an increase in the number of patients with the chronic disease, according to the most...
by European Society of Cardiology Credit: Unsplash/CC0 Public Domain Women with atrial fibrillation progress more rapidly to cognitive impairment and dementia than men with the heart rhythm condition, according to research presented today at ACNAP 2023, a scientific congress of the European Society of Cardiology (ESC) and published in the journal Alzheimer’s & Dementia. “Symptoms of atrial fibrillation in women are...
by Kathryn F. Sykes, Medical Xpress Cancer is the result of the uncontrolled division and spread of cells into surrounding tissue. Recently researchers have begun to focus on biomarkers as a source of information about different cancers, how they work in the body, and how they can be fought. Credit: Colin Behrens/Pixabay, CC0 Public Domain One of...
by CU Anschutz Medical Campus Credit: Pixabay/CC0 Public Domain An article published in the Lancet Neurology journal evaluates the risk of recurrence of active disease in older patients with multiple sclerosis after discontinuing disease-modifying therapies. Multiple sclerosis (MS) is a chronic illness, often presenting in young adulthood. Most commonly, at onset, individuals have acute attacks, or relapses,...
by Universitätsmedizin Magdeburg Graphical summary of inflammatory cell death induction of MHC-deficient and IFN-unresponsive tumors by CD4+ T cells in cooperation with iNOS-expressing myeloid cells. Credit: Nature (2023). DOI: 10.1038/s41586-023-06199-x An interdisciplinary team of researchers at the Otto-von-Guericke University in Magdeburg has gained new insights into how inflammatory mediators of pathogen defense can remotely drive cancer cells into death—an...
