by Lori Solomon The U.S. Food and Drug Administration has approved Takeda Pharmaceuticals Adzynma, the first recombinant protein product indicated for prophylactic or on-demand enzyme replacement therapy (ERT) in adult and pediatric patients with congenital thrombotic thrombocytopenic purpura (cTTP). Adzynma is a purified recombinant form of the ADAMTS13 enzyme that enhances the low levels of...
by King’s College London Credit: CC0 Public Domain Eating in a ten-hour window is associated with higher energy and mood and lower hunger levels, new results from the largest UK community science study of its kind shows. Results from the trial are presented today by researchers from King’s College London at the European Nutrition Conference in...
by Jordan Clay, University of Kentucky Credit: Pixabay/CC0 Public Domain Epilepsy is a common neurological condition which leads to seizures. It affects millions of people in the United States and tens of millions worldwide. It’s important to know what epilepsy is, how to recognize what happens during a seizure, and how to provide first aid when...
by Hokkaido University (Top) Cancer stem cells produce interleukin-6 (IL-6), which induces senescence in macrophages (Mφ). In turn, these produce arginase-1 and inactivate T cells. As a result, cancer cells are not killed by immune system cells, leading to tumor formation. (Bottom) Non-cancer stem cells do not produce IL-6. Macrophages do not age and T cells...
by University of British Columbia Credit: CC0 Public Domain A special kind of genetic test that helps determine the best antidepressant for patients with moderate-to-severe depression could generate substantive health system savings and greatly improve patient outcomes, according to new research from the University of British Columbia. The study, published today in the Canadian Medical Association...
by The Mount Sinai Hospital Artistic representation of the gene clusters that influence cancer progression in Drs. Xu and Zhang’s latest research study in Genome Research. Credit: Mount Sinai Health System Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a study identifying 4,749 key gene clusters, termed “prognostic modules,” that significantly influence...
by Carole Tanzer Miller The gap in life expectancy between American men and women is now the biggest it has been since the mid-1990s—almost six years. The pandemic and opioid overdoses are key factors in the gender difference in longevity, said researchers from the University of California, San Francisco (UCSF) and Harvard University T.H. Chan...
by American Heart Association Credit: CC0 Public Domain Electrocardiogram (EKG) based screening using an artificial intelligence-enabled digital stethoscope may detect peripartum cardiomyopathy, a disease of the heart muscle in pregnant and recently pregnant women, at double the rate of standard obstetric care including clinical EKGs, according to late-breaking science presented today at the American Heart Association’s...
by University of Oxford Credit: Pixabay/CC0 Public Domain An AI tool that can predict 10-year risk of deadly heart attacks could transform treatment for patients who undergo CT scans to investigate chest pain, according to research presented today at the American Heart Association’s Scientific Sessions in Philadelphia. In the first real-world trial of the AI tool,...
by American College of Physicians Credit: CC0 Public Domain A randomized controlled trial that included more than 300 people diagnosed with chronic spontaneous urticaria (CSU)—hives—has found that acupuncture may offer limited relief from the condition, but clinical significance of this finding was unclear. The study is published in Annals of Internal Medicine. CSU is the most...
