by Mass General Brigham Credit: Pixabay/CC0 Public Domain Intratumoral therapy—in which cancer drugs are injected directly into tumors—is a promising treatment option for solid cancers but has shown limited success in clinical trials due to an inability to precisely deliver the drug and because most immunotherapies quickly dissipate from the site of injection. A team of...
Month: <span>November 2023</span>
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New anti-clotting medication found to reduce bleeding among people with atrial fibrillation
by American Heart Association Credit: Pixabay/CC0 Public Domain An experimental anti-clotting medication, abelacimab, significantly reduced bleeding among people with atrial fibrillation (or AFib) who were at risk of stroke, according to results of the AZALEA-TIMI 71 trial, presented today as late-breaking science at the American Heart Association’s Scientific Sessions 2023. The meeting, held Nov. 11–13, in...
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Medical researchers show AI can easily generate large volumes of health-related disinformation
by Flinders University Credit: CC0 Public Domain Government and industry guardrails are urgently needed for Generative AI to protect the health and well-being of our communities, say Flinders University medical researchers who put the technology to the test and saw how it failed. Rapidly evolving Generative AI, the cutting-edge domain prized for its capacity to create...
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Discovered the epigenetic scars that the COVID-19 disease causes in the lung
Peer-Reviewed Publication JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE MANEL ESTELLER, VERONICA DAVALOS, ALEIX NOGUERA-CASTELLS AND EVA MUSULEN, JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE. AUTHORS OF THE STUDY ABOUT THE EFFECT OF LETHAL COVID-19 IN THE EPIGENETICS OF THE LUNG TISSUES CREDIT: JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE. The COVID-19 disease, due to infection with the SARS-CoV2 virus, became...
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Shedding new light on sugars, the “dark matter” of cellular biology
Peer-Reviewed Publication UNIVERSITY OF MONTREAL “OUR IDEA WAS TO LABEL SUGAR MOLECULES WITH A CHROMOPHORE, A CHEMICAL THAT GIVES A MOLECULE ITS COLOUR,” EXPLAINED CECIONI. “THE CHROMOPHORE IS ACTUALLY FLUOROGENIC, WHICH MEANS THAT IT CAN BECOME FLUORESCENT IF THE BINDING OF SUGAR WITH THE LECTIN IS EFFICIENTLY CAPTURED.” CREDIT: CECIONI LAB Scientists at Université de...
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Purdue pharmaceutical compound sounds the alarm on cancer cells and unleashes T cells
College of Pharmacy researchers develop small-molecule degrader to target enzyme that plays a role in tumor cells and the immune system Peer-Reviewed Publication PURDUE UNIVERSITY ZHONG-YIN ZHANG OF PURDUE UNIVERSITY’S COLLEGE OF PHARMACY AND THE PURDUE INSTITUTE FOR DRUG DISCOVERY LEADS A TEAM THAT HAS CREATED A NOVEL CANCER IMMUNOTHERAPY COMPOUND THAT DEGRADES AN ENZYME...
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Making AI Smarter with an Artificial, Multisensory Integrated Neuron
Posted Today Artificial neuron processes visual and tactile input together. The feel of a cat’s fur can reveal some information, but seeing the feline provides critical details: Is it a housecat or a lion? While the sound of fire crackling may be ambiguous, its scent confirms the burning wood. Our senses synergize to give a comprehensive...
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Women with depression have 20% lower taurine concentration in the hippocampus
Precise observation using ultra-high magnetic field 7T MRIPeer-Reviewed Publication NATIONAL RESEARCH COUNCIL OF SCIENCE & TECHNOLOGY (A) BRAIN REGIONS WHERE SPECTRA WERE MEASURED (YELLOW BOX) (B) 1H MR SPECTRUM IN THE HIPPOCAMPUS: HIPPOCAMPAL TAURINE SIGNAL SHOWN AT 3.4 PPM (ARROW). BLACK LINE: ACTUAL MEASURED SPECTRUM. RED LINE: LCMODEL FITTING SPECTRUM. ABBREVIATION: TAU, TAURINE; CHO, CHOLINE;...
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DISCOVERY GETS US CLOSER TO ‘MUSCLE IN A DISH’
NOVEMBER 14TH, 2023POSTED BY UC IRVINE One disorder the Hicks lab hopes to treat with their lab-grown muscle progenitors is tears to the rotator cuff muscles, which affects up to 30% of people over the age of 65. (Credit: Getty Images) Researchers have identified a gene expressed during regeneration that is critical for muscle repair. The key...
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Early Detection and Gender Disparities in COPD
In this interview, Dr. MeiLan Han, a distinguished pulmonologist and Chief of the Division of Pulmonary and Critical Care at the University of Michigan, shares her profound insights into Chronic Obstructive Pulmonary Disease (COPD).With your extensive background and contributions in Pulmonary and Critical Care, can you share what initially drew you to the study of...