Month: <span>November 2023</span>

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Earlier onset of atrial fibrillation linked to risk of developing all-cause dementia
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Earlier onset of atrial fibrillation linked to risk of developing all-cause dementia

by Elana Gotkine Credit: CC0 Public Domain Earlier onset of atrial fibrillation (AF) is associated with increased risk of developing all-cause dementia, vascular dementia (VD), and Alzheimer disease (AD), according to a study published online Nov. 8 in JAMA Network Open. Wenya Zhang, from the Chinese Academy of Medical Sciences & Peking Union Medical College...

New approach to pancreatic cancer treatment expands therapeutic possibilities, shows promise for increased survival
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New approach to pancreatic cancer treatment expands therapeutic possibilities, shows promise for increased survival

by Virginia Commonwealth University Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domain Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer. Researchers from VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM)...

Study finds tapering TNF inhibitors increases flares, lowers Boolean remission rates for RA patients in remission
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Study finds tapering TNF inhibitors increases flares, lowers Boolean remission rates for RA patients in remission

by American College of Rheumatology Credit: Unsplash/CC0 Public Domain New research at ACR Convergence 2023, the American College of Rheumatology’s (ACR) annual meeting, has found that rheumatoid arthritis (RA) patients in sustained remission who stopped TNF inhibitors (TNFi) had significantly more flares and lower Boolean 2.0 remission rates compared with those who continued treatment. Boolean 2.0...

Study shows stem cell transplant significantly improves outcomes in refractory juvenile systemic sclerosis
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Study shows stem cell transplant significantly improves outcomes in refractory juvenile systemic sclerosis

by American College of Rheumatology Credit: CC0 Public Domain New research at ACR Convergence 2023, the American College of Rheumatology’s (ACR) annual meeting, shows that patients with refractory juvenile systemic sclerosis improved significantly on nearly all measures for two years following autologous stem cell transplant.Juvenile-onset systemic sclerosis (jSSc), also called scleroderma, is a disfiguring autoimmune disorder...

Research links sleep apnea to increased risk of atrial fibrillation
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Research links sleep apnea to increased risk of atrial fibrillation

by Cleveland Clinic 12 lead ECG showing atrial fibrillation at approximately 150 beats per minute. Credit: James Heilman, MD/Wikipedia/CC BY-SA 3.0 New research from Cleveland Clinic has identified a link between sleep apnea and the development of atrial fibrillation, a common heart rhythm disorder. Published in the Journal of the American Heart Association, the study of...

Wegovy cuts risk of heart attacks in milestone cardiovascular trial
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Wegovy cuts risk of heart attacks in milestone cardiovascular trial

By Elaine Chen This image provided by Novo Nordisk in January 2023, shows packaging for the company’s Wegovy drug.NOVO NORDISK VIA AP PHILADELPHIA — Novo Nordisk’s obesity drug Wegovy notably cut the risk of heart attacks in a landmark cardiovascular trial that affirms the treatment offers health benefits beyond weight loss. The company in August had...

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‘Hidden’ Cognitive Impairments in DMD May Worsen Outcomes

Jim Kling November 08, 2023 Cognitive issues in children with Duchenne muscular dystrophy (DMD) are linked to worse outcomes, but limited access to specialists and limited resources make this problem difficult to address. A new tool from the National Institutes of Health, called NIH Toolbox, could improve that outcome, according to Mathula Thangarajh, MD, PhD, who has...

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Duchenne Muscular Dystrophy Gene Therapy Safe, Effective at 4 Years

Nancy A. Melville November 06, 2023 PHOENIX — Children with Duchenne muscular dystrophy (DMD) treated with the only gene therapy to date to be approved for treatment of disease in the United States show sustained maintenance of motor function after 4 years, compared with untreated patients who showed significant decline over the same time period, new research...

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Fully synthetic genome nears completion in a step toward unraveling genetic mysteries

A micrograph of one of Jef Boeke’s yeast strains with a partially synthetic genome (Credit: Yu Zhao, NYU Langone Health)November 9, 2023 07:11 AM EST R&DDiscoveryIn FocusFully synthetic genome nears completion in a step toward unraveling genetic mysteriesRyan CrossSenior Science CorrespondentAn international effort to create yeast cells with a fully synthetic genome is nearing completion,...

Scientists invent new method to regenerate muscle tissue   
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Scientists invent new method to regenerate muscle tissue   

by University of Waterloo Cell sheets are guided to form anchored, scaffold-free constructs for in vitro modeling by providing pillars that act as anchors for otherwise anchorless cell sheets. Credit: Advanced Functional Materials (2023). DOI: 10.1002/adfm.202308552 People who have experienced significant muscle damage have new hope thanks to Evolved.Bio, a startup that has developed innovative technology...