by Wiley Credit: Pixabay/CC0 Public Domain Buprenorphine is a medication approved for pain and opioid dependence. New findings published in The American Journal on Addictions indicate that a transmucosal dose (which dissolves in the mouth) of buprenorphine followed by an injection of extended-release buprenorphine (BUP‐XR) may be an effective treatment for individuals with opioid use disorder...
Are some children genetically predisposed to poor sleep?
by Wiley Credit: Pixabay/CC0 Public Domain Previous research has identified genetic variants associated with insomnia and sleep duration in adults. Now a study published in the Journal of Child Psychology and Psychiatry has found that these variants also likely affect sleep quality and quantity in children. In the study of 2,458 children of European ancestry, children...
Does being a caregiver affect older women’s longevity?
by Wiley Credit: Pixabay/CC0 Public Domain In an analysis published in the Journal of the American Geriatrics Society that included older US women, caregiving was associated with a lower risk of death over an average follow-up of 17.5 years. In the analysis of 158,987 women aged 50–79 years when enrolled in the Women’s Health Initiative (a...
Scientists engineer potent immune cells for ‘off-the-shelf’ cancer immunotherapy
by University of California, Los Angeles Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAID UCLA scientists have developed a new method to engineer more powerful immune cells that can potentially be used for “off-the-shelf” cell therapy to treat challenging cancers. “Off-the-shelf”...
Researchers identify brain network that is uniquely activated through injection vs. oral drug use
by National Institutes of Health Credit: CC0 Public Domain Results from a new clinical trial suggest that a group of brain regions known as the “salience network” is activated after a drug is taken intravenously, but not when that same drug is taken orally. When drugs enter the brain quickly, such as through injection or smoking,...
Stacking your exercise over the weekend as effective as spreading activity out
by Alex Osiadacz, Mayo Clinic News Network Credit: CC0 Public Domain Researchers have found that condensing exercise into a few days is as effective as spreading activity out across a week. Dr. Wes Troyer, a Mayo Clinic physical medicine and rehabilitation physician, explains how people who stack their workouts can avoid common injuries and reap...
Nonsurgical treatment for uterine fibroids
by Sonya Goins, Mayo Clinic News Network Credit: Pixabay/CC0 Public Domain Uterine fibroids are the leading cause of women undergoing hysterectomies, leaving them unable to bear children. Fibroids often are diagnosed in women between 20 and 40. They can cause heavy menstrual bleeding, pain and infertility. Dr. Michelle Louie, a Mayo Clinic gynecologic surgeon and...
Consuming flavonoids helps fight symptoms of endometriosis, researchers find
by Courtney Price, Texas A&M University Credit: Pixabay/CC0 Public Domain Researchers at Texas A&M University’s School of Veterinary Medicine and Biomedical Sciences (VMBS) have found a correlation between a compound found in fruits and vegetables and a reduction in the symptoms of endometriosis. In an article published in the journal Endocrinology, the researchers outline how flavonoids...
FDA approves Voquezna for erosive esophagitis, GERD
by Lori Solomon The U.S. Food and Drug Administration has approved Phathom Pharmaceuticals’ Voquezna (vonoprazan), a novel potassium-competitive acid blocker, as a new treatment for adults for with all grades of erosive esophagitis or erosive gastroesophageal reflux disease (GERD). The approval is based on the results of the PHALCON-EE Phase III trial, in which Voquezna...
Real-Time CGM Plus Insulin Pump Best for Type 1 Diabetes
Miriam E. Tucker Youth with type 1 diabetes who use real-time continuous glucose monitoring (rtCGM) and an insulin pump spend more time in target glucose range than those using intermittently scanned CGM (isCGM) and/or multiple daily insulin injections, new data show. In the multinational cohort study of more than 4500 people younger than age 21...