by American College of Rheumatology Credit: CC0 Public Domain Researchers will present the first-ever study of fractures and calcium pyrophosphate deposition disease at ACR Convergence 2023, the American College of Rheumatology’s (ACR) annual meeting. They report a doubled risk of fractures in patients with acute calcium pyrophosphate crystal arthritis compared to those without the disease. Calcium...
Study supports use of reduced-dose of direct oral anticoagulants for many older adults with two or more conditions
by Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging Research Association of standard‐ vs reduced‐dose direct oral anticoagulants on outcomes. Detailed event rates, individuals at risk, and follow‐up times are presented in Table S6. IPTW indicates inverse probability treatment‐ and inverse probability censor‐weighted. Credit: Journal of the American Heart Association (2023). DOI: 10.1161/JAHA.122.029865 A...
Study finds hydroxychloroquine lowers risk of nonalcoholic fatty liver disease in rheumatoid arthritis patients
by American College of Rheumatology Credit: Pixabay/CC0 Public Domain New research at ACR Convergence 2023, the American College of Rheumatology’s (ACR) annual meeting, shows that treating rheumatoid arthritis with hydroxychloroquine (HCQ) reduced the risk of nonalcoholic fatty liver disease, especially in women and men who are 50 years old and younger. Rheumatoid arthritis (RA) is a...
Long COVID in women may be linked to inflammation levels at peak of infection, new research suggests
by University of York Credit: Unsplash/CC0 Public Domain Women who have mild inflammation in the acute stages of COVID-19 infection may be more likely to experience a particular set of long COVID symptoms, according to new research. The study, carried out by clinical researchers at the University of York, Hull York Medical school (HYMS) and the...
Previous genetic association studies involving people with European ancestry may be inaccurate
by NIH/National Human Genome Research Institute Researchers have found that previous studies analyzing the genomes of people with European ancestry may have reported inaccurate results by not fully accounting for population structure. Credit: Darryl Leja, National Human Genome Research Institute Researchers have found that previous studies analyzing the genomes of people with European ancestry may have...
Beware of Popular Online Liver Supplements, Doctors Say
Damian McNamara, MA November 06, 2023 The 10 best-selling liver health supplements on Amazon bring in an estimated $2.5 million each month. But none of them contain ingredients recommended by major groups of doctors who treat liver issues in the United States or Europe. Like many supplements, popular online liver products are unregulated, meaning they...
mRNA’s next trick? Reprogramming off-the-shelf cell therapies for cancer and autoimmune diseases
mRNA’s next trick? Reprogramming off-the-shelf cell therapies for cancer and autoimmune diseasesRyan CrossSenior Science CorrespondentLei Lei WuNews ReporterA handful of biotechs, including Moderna, are betting that simple infusions with mRNA could supercharge immune cells to fight cancer and other diseases in what would be a fresh take on CAR-T cell therapies.Instead of collecting a patient’s...
New study projects continued rise in most common liver disease
Liver doctors change how they talk about liver disease as cases climb Reports and Proceedings AMERICAN ASSOCIATION FOR THE STUDY OF LIVER DISEASES Boston (Nov. 7, 2023) — The most common form of chronic liver disease is expected to steadily rise over the next 25 years, adding significant burden to the medical system as a...
Pancreas ‘crosstalk’ may influence course of type 1 and type 2 diabetes
by Bill Snyder, Vanderbilt University Method for quantification of ADM lobules. ADM-positive lobules (outlined in green) were tallied per section. Total pancreatic tissue (orange) was outlined manually and quantified. ADM score was determined by dividing the total number of ADM-positive lobules (across head, body, and tail regions) by the total tissue area. Scale bar = 2mm....
Boosting immune system in chronic myeloid leukemia may lead to discontinuation of blood cancer drugs
by University of Helsinki Schematics showing the overview of data sets, analysis, and validation and extensions. Picture created with biorender.com. Credit: Leukemia (2023). DOI: 10.1038/s41375-023-02074-w In a recent study published in Leukemia, Finnish researchers investigated why some patients with chronic myeloid leukemia (CML) can discontinue their daily medication safely. CML, one of the four main types...