by Kimbra Cutlip, University of Maryland Expression and characterization of the Spike and prefusion Spike-Fc (S-Fc) protein. a Schematic illustration of the full-length protein sequence of SARS-CoV-2 Spike. SP: signal peptide; RBD: receptor binding domain; TM: transmembrane domain; CT: cytoplasmic tail. Graphic design of the fusion of SARS-CoV-2 Spike with the T4 fibritin foldon domain (Fd)...
Poor night’s sleep can trigger atrial fibrillation the next day
by University of California, San Francisco Credit: Unsplash/CC0 Public Domain We all know that a lousy night’s sleep can leave us feeling drained the next day. Now a study by UC San Francisco has found another reason to catch more Z’s: poor sleep is tied to significantly higher odds of experiencing atrial fibrillation (A-Fib)—irregular heartbeats that...
The dual role of well-known protein sheds light on Parkinson’s disease mechanisms
by Lisbeth Heilesen, Aarhus University New research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in the cell membrane. Credit: Antoni Kowalski The protein alpha-synuclein (aSN) has long been known as a main cause in Parkinson’s disease and Lewy Body Dementia, for example, when it forms lumpy protein...
An immune molecule that regulates aging and a living organism’s lifespan
by Ingrid Fadelli , Medical Xpress The expression of IM33 in fly brain. Blue: Dapi, which labels the nucleus of all the cells. Magenta: IM33 positive cells. Credit: Xu et al. Aging is a natural process that affects all living organisms, prompting gradual changes in their behavior and abilities. Past studies have highlighted several physiological...
Your biological age predicts dementia and stroke regardless of your actual age—new study
by Jonathan Ka Long Mak and Sara Hägg, The Conversation Credit: CC0 Public Domain As we journey through life, the risk of developing chronic diseases, including cancer, heart disease and neurological disorders, increases significantly. However, while we all grow older chronologically at the same pace, biologically, our clocks can tick faster or slower. Relying solely on...
Depression, anxiety and stress linked to poor heart health in two new studies
by American Heart Association Credit: Unsplash/CC0 Public Domain The heart and mind are strongly connected, with depression, anxiety and chronic stress all increasing the risk for heart and brain health complications, according to two preliminary studies to be presented at the American Heart Association’s Scientific Sessions 2023, held Nov. 11–13, in Philadelphia. Mental health conditions, including depression,...
Marijuana use linked with increased risk of heart attack, heart failure
by American Heart Association Credit: Unsplash/CC0 Public Domain Using marijuana regularly may raise the risk for heart failure, stroke or heart attack even after accounting for other cardiovascular risk factors such as Type 2 diabetes, high blood pressure and obesity, according to two preliminary studies to be presented at the American Heart Association’s Scientific Sessions 2023. The...
American Indian and Alaska Native adults had higher rate of premature heart attack deaths
by American Heart Association Karthik Gonuguntla et al, Proportionate Mortality of Premature Myocardial Infarction in American Indians and Alaska Natives in the USA From 1999-2020. https://www.abstractsonline.com/pp8/?_ga=2.17782015.7532578.1693882428-1949139275.1663003561#!/10871/presentation/12322 American Indian and Alaska Native adults had significantly higher heart attack death rates at younger ages compared to adults in other racial and ethnic group, according to preliminary research to be presented...
A vitamin K–rich diet may help protect your health as you age. Experts suggest these 9 foods
ALEX VANCE November 4, 2023 at 7:00 AM Alexander Spatari via Getty Images Whether you snag some vitamin C at the first sign of a cold or stock up on probiotics to keep your gut health in check, you’re not alone in turning to dietary supplements—an estimated 75% of Americans use them. Among the various...
Can Fructose Lead To Weight Gain? Here Are Other Downsides Of Consuming Fructose
Here we list the negative impacts of consuming fructose and how it can lead to other health issues besides weight gain. Manya Singh It’s important to note that fructose found naturally in whole fruits is generally not a concern Fructose is a naturally occurring sugar found in fruits, honey, and some vegetables. It is also...