Maurie Markman, MDDISCL OSURES October 04, 2023 I’m Dr Maurie Markman from City of Hope, and I would like to discuss a fascinating, long-term, follow-up study of a trial that was completed many years ago but addresses a very important, clinically related matter. The trial I am referring to, published in the Journal of Clinical Oncology, is...
Month: <span>November 2023</span>
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Citrus compounds show zesty promise in type 2 diabetes management
By Dr. Sanchari Sinha Dutta, Ph.D.Nov 2 2023 Study: A systematic review exploring the mechanisms by which citrus bioflavonoid supplementation benefits blood glucose levels and metabolic complications in type 2 diabetes mellitus. Image Credit: siam.pukkato / ShutterstockStudy: A systematic review exploring the mechanisms by which citrus bioflavonoid supplementation benefits blood glucose levels and metabolic complications...
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Researchers find evidence of mpox circulating in humans since 2016
by Bob Yirka , Medical Xpress Estimating the time of MPXV emergence into the human population from the accumulation of APOBEC3-type mutations. (A) MPXV genomes sampled from human infections from 2017 to 2022, with an outgroup sequence from an outbreak in Nigeria in 1971 Mutations along each branch are indicated with circles colored by whether...
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Beta-cells study sheds light on cause of type 2 diabetes
by Johns Hopkins University Immuno staining of endogenous INSULIN (cyan), PITPNA (green), and protein markers (magenta) for the Golgi (GIANTIN), ER (CALR), and intracellular granules (CD63) in pancreatic islets isolated from a non-diabetic human subject. White arrows denote the colocalization of protein markers with PITPNA. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-39978-1 Scientists at Johns Hopkins All...
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Checking for counterfeit medication using a smartphone
by Sandra Mehlhase, Fraunhofer-Gesellschaft At MEDICA 2023, the Fraun-hofer team will exhibit a demonstration version of the SmartID counterfeit-proof barcode system. Credit: Fraunhofer-Gesellschaft When it comes to medication or medical devices sold online, end-users often wonder whether these are real or fake. The SmartID counterfeit-proof barcode system means anyone can use a smartphone to check a...
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New study calls into question the superiority of stem cell therapy for treating knee pain
by Brian Katzowitz, Emory University Credit: Pixabay/CC0 Public Domain Characterized by extensive damage to joints and debilitating pain, osteoarthritis (OA) impacts millions of people worldwide and has long posed a substantial clinical and economic burden. In spite of advances in diagnosis, medications, and short-term pain management solutions, the elusive goal of a disease-modifying OA drug has...
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Study analyzes recent global and national trends of atherosclerosis
by Cactus Communications Joinpoint regression analysis of global PAD prevalence (A), incidence (B), mortality rate (C), and DALYs (D) in adults ≥20 years of age from 1990 to 2019. * P <0.05. APC: Annual percentage change; DALYs: Disability-adjusted life years; PAD: Peripheral arterial disease. Credit: Chinese Medical Journal (2023). DOI: 10.1097/CM9.0000000000002839. Cardiovascular diseases are a...
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Different antibiotics’ effects on gut microbes may impact hypertensive organ damage
by American Society of Nephrology Credit: Pixabay/CC0 Public Domain New research in rodents indicates that altering gut microbes may affect the development of organ damage associated with hypertension. The findings will be presented at ASN Kidney Week 2023, November 1–5. For the study, scientists used narrow-spectrum antibiotics to specifically deplete Gram-negative or Gram-positive bacteria in rats...
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Are sodium-glucose cotransporter-2 inhibitors safe for patients with diabetes and cancer?
by American Society of Nephrology Credit: Pixabay/CC0 Public Domain Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have heart- and kidney-related benefits for patients with and without diabetes that go beyond their initial indication for lowering blood sugar levels. In clinical trials, the risk of serious adverse events with SGLT2i has been low, but the safety outcomes of SGLT2i in...
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Cross-subject emotion recognition brain-computer interface based on fNIRS and DBJNet
by Beijing Institute of Technology Press Co. Cross-subject emotion recognition framework based on fNIRS, including data collection, data partitioning, model training and evaluation. Credit: Cyborg and Bionic Systems Emotion recognition based on neural signals is leading the revolution of affective science. By analyzing brain activity, we can glimpse the secrets of the human inner world....