by Duke-NUS Medical School Credit: Cell Metabolism (2023). DOI: 10.1016/j.cmet.2023.08.001 Scientists from Duke-NUS Medical School, in collaboration with counterparts from Columbia University, have developed a new framework to measure metabolic health. The concept of “metabolic elasticity” paints a more comprehensive picture of how the body reacts to changes in the availability of food and how efficiently...
Circuit-specific gene therapy brings new hope for treatment of Parkinson’s disease
by Chinese Academy of Sciences Retrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIAT Researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and their collaborators have developed a gene therapy strategy to selectively manipulate Parkinson’s disease-affected circuitry and attenuate the core motor symptoms...
Research identifies signaling mechanism that suppresses depressive symptoms caused by daily stress
by Korea University College of Medicine LHb D-neurons project to RMTg GABAergic neurons and are activated by acute stress. Acute stress evokes trace amine release from LHb D-neurons to RMTg GABAergic neurons, leading to neuronal inactivation via TAAR1-mediated trace aminergic signaling. As the effect of trace amines overrides the excitatory glutamatergic transmission, LHb D-neurons act...
First Pill for Dengue Shows Promise in Human Challenge Trial
By Jennifer Rigby October 23, 2023 (Reuters) – A pill for dengue fever developed by Johnson & Johnson appeared to protect against a form of the virus in a handful of patients in a small human challenge trial in the United States, according to data presented by the company on Friday. There are currently no specific treatments...
Exercise as Good as Viagra for ED: Study
Courtney Southwick October 23, 2023 Exercising for at least 30 minutes three times a week can be just as effective as Viagra and similar medications at improving erectile function, according to a new analysis of the best research to date on aerobic exercise and erectile function. The study, published this month in The Journal of Sexual Medicine,...
Smart Bracelet May Predict Mood Changes in Bipolar Disorder
Liam Davenport October 12, 2023 Electrodermal activity (EDA) measured via a smart bracelet/wristband may help predict and track changes in mood and more rapidly assess treatment response in patients with bipolar disorder (BD), early research suggests. In a small observational pilot study, researchers found the E4 wristband (Empatica, Inc) was able to detect fluctuations in mood. The...
Google looks to ultrasound to monitor heart rate through ANC headphones
Google looks to ultrasound to monitor heart rate through ANC headphonesBy Paul RiddenOctober 31, 2023 Google researchers have developed a system that can transform any TWS ANC wearables into heart rate monitors via a software updateSmartwatches that can monitor a wearer’s heart rate use light pulses to detect changes in blood volume. But research from...
Psychedelic treatments are speeding towards approval — but no one knows how they work
Many questions remain about the formerly taboo chemicals that are being used to treat trauma and depression. Sara Reardon Psychedelic treatments are speeding towards approval — but no one knows how they workMany questions remain about the formerly taboo chemicals that are being used to treat trauma and depression. Conceptual illustration showing an abstract brain....
HEALTH ECONOMISTS: COVID VAX CAMPAIGN SAVED 2.4 MILLION LIVES
NOVEMBER 1ST, 2023POSTED BY CORRIE PIKUL-BROWN Empty vials of the Pfizer/BioNTech Comirnaty vaccine against COVID-19 at a vaccination center at the Messe trade fair grounds during the third wave of the coronavirus pandemic on April 8, 2021 in Erfurt, Germany. The global COVID-19 vaccination campaign saved 2.4 million lives in 141 countries and could have saved...
From Space to Your Face: Less Wrinkles
After surviving the cosmic radiation and extreme temperatures of 18 months in space, an organism first identified by NASA decades ago is now improving sunscreens and anti-aging products. Skin care – illustrative photo. Image credit: Pixabay (Free Pixabay license) Bacillus Lysate, which doesn’t actually contain any live bacteria, is a skincare additive derived from Bacillus...