by University of Montreal CD47 interacts in cis with SLAMF7 on tumor cells. a, Binding of CD47-Fc (red line) to WT or Sirpa−/− BMDMs assayed by flow cytometry. Filled curves, Ctrl Fc. b, Mass spectrometry analysis of Flag mAb immunoprecipitates from L1210 derivatives expressing a Flag-tagged variant of mCD47 showing various potentially associated proteins. c, Co-IP...
Kathrin LaFaver, MD; Meredith Wicklund, MDDISCLOSURES This transcript has been edited for clarity. Kathrin LaFaver, MD: Hi. My name is Kathrin LaFaver. I’m a neurologist in Saratoga Springs, New York. I’ll be talking on behalf of Medscape today with Dr Meredith Wicklund, who is a senior associate consultant and behavioral neurologist specialist at Mayo Clinic...
Vincent Richeux PARIS — Most diarrhea that leads patients to seek medical advice is actually a false alarm, said gastroenterologist Nassim Hammoudi, MD, PhD, of the Lariboisière Hospital in Paris, during France’s annual general medicine conference (JNMG 2023). He said that doctors need to understand the characteristics of chronic diarrhea and adapt its management accordingly....
Sara Freeman Primary care practitioners have an important role to play in helping to diagnose people with axial spondyloarthritis (axSpA) much sooner than is currently being achieved, according to several experts who are championing the need for the earlier diagnosis of the condition. AxSpA is an inflammatory condition of the spine and joints that often...
by Ohio State University Medical Center Prepackaged pouches of nicotine, flavoring, artificial sweetener and other chemicals are rising in popularity as an alternative to cigarettes. While oral nicotine pouches have fewer carcinogens than cigarettes, a new study by The Ohio State University Comprehensive Cancer Center’s Center for Tobacco Research finds they do not curb nicotine cravings...
by Lund University Credit: Pixabay/CC0 Public Domain A man who is exposed to physical pain feels less severe pain if he is subjected to pain by a woman compared with a man, according to new research from Lund University in Sweden. In addition, men experience less pain after surgery when asked about it by a woman...
by Jim Stallard, Memorial Sloan Kettering Cancer Center Credit: Pixabay/CC0 Public Domain CAR T cell therapy, a powerful type of immunotherapy, has begun to revolutionize cancer treatment. Pioneered at Memorial Sloan Kettering Cancer Center (MSK), the therapy involves engineering a patient’s T cells so they recognize and attack cancer cells. These CAR (chimeric antigen receptor) T...
by Physicians Committee for Responsible Medicine Graphical Abstract. Credit: Complementary Therapies in Medicine (2023). DOI: 10.1016/j.ctim.2023.103002 A low-fat vegan diet that includes soy fosters changes in the gut microbiome that decrease postmenopausal vasomotor symptoms, or hot flashes, overall by 95%, according to a new study by the Physicians Committee for Responsible Medicine. A vegan diet...
by Jacqueline Mitchell, Beth Israel Deaconess Medical Center Generation and characterization of Usp30 KO mice. a Schematic of gene targeting to generate the Usp30 KO mice. b Bar graph shows the levels of Usp30 gene expression in different tissues in Usp30 WT and KO mice (n = 5 for brain, n = 4 for testis, n = 3 for all other tissues)....
by Lindsay Travis, University of Kentucky Single-particle 3D reconstruction of the C-zone reveals the organization of titin, cMyBP-C and myosin heads and tails. Credit: Nature (2023). DOI: 10.1038/s41586-023-06691-4 One University of Kentucky (UK) researcher has helped solve a 60-year-old mystery about one of the body’s most vital organs: The heart. Kenneth S. Campbell, Ph.D., the director...
