by Mallory Locklear, Yale University Credit: Michael S. Helfenbein In cases of opioid use disorder, short-term medically managed withdrawal (commonly known as detox) and long-term rehabilitation treatments that don’t incorporate continued use of buprenorphine or methadone are no more effective at preventing overdose deaths than no treatment at all, a new Yale-led study reveals. The findings,...
by Impact Journals LLC Experimental design for the results shown in Figures 3 and 4. Credit: 2023 Copp et al. A new research paper titled “Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes” has been published in Aging. While advanced age is widely recognized as the greatest risk...
by Josh Barney, University of Virginia Tau proteins are prime suspects in Alzheimer’s and other neurodegenerative disorders. New UVA research could open doors to future treatments. Credit: Emily Faith Morgan / University of Virginia Communications Alzheimer’s disease researchers at the University of Virginia have discovered how harmful tau proteins damage the essential operating instructions for our...
by UC Davis Credit: Unsplash/CC0 Public Domain The Food and Drug Administration (FDA) has recalled dozens of over-the-counter lubricating eye drops and artificial tears in 2023 due to contamination and unsafe manufacturing practices. The recalls began in February, when three brands were withdrawn, including one linked to serious infections, vision loss and four deaths. Additional recalls...
by British Medical Journal Credit: Pixabay/CC0 Public Domain The diabetes drug dulaglutide (Trulicity) may significantly lower a woman’s risk of substantial weight gain after she has given up smoking, finds a secondary analysis of clinical trial data, published in the open access journal BMJ Nutrition Prevention & Health. Women seem to be five times as likely...
by European Respiratory Society Credit: Pixabay/CC0 Public Domain A 12-week course of daily beetroot juice supplement for people with chronic obstructive pulmonary disease (COPD) lowered blood pressure and improved how far patients could walk in six minutes in research published in the European Respiratory Journal. COPD is a serious lung condition affecting around 400 million...
by Karolinska Institutet Credit: CC0 Public Domain Statins could slow the progression of Alzheimer’s disease, at least for some patients. This is the result of a new study led by Karolinska Institutet published in Alzheimer Research and Therapy. But the researchers are cautious in their interpretations and see the results as a first step in a...
by Jason Howland, Mayo Clinic News Network Credit: Unsplash/CC0 Public Domain The holidays are a joyous occasion for most people. But for someone with cancer or other serious illness, it can be a time of overwhelming anxiety and fear. And as family and friends get together, it’s important to show that you care without coming...
by Holly Moody-Porter, University of Maryland School of Medicine Credit: Yash Lucid from Pexels The widespread use of cannabis (marijuana) and its increased potency are associated with a rise in cannabis-related psychiatric conditions, according to a new University of Maryland School of Medicine (UMSOM) review article that was published in the New England Journal of Medicine....
by Perelman School of Medicine at the University of Pennsylvania PBA treatment reduces PERK activity and increases XBP1s in the hippocampus of APPNL-G-F knock-in (KI) mice. Confocal images of the hippocampus across groups. (A) BiP in the CA3. (B) p-PERK in the CA3. (C) ATF4 in the CA1. (D) XBP1s in the CA3. (E) ADAM10 in...
