by Virginia Singla, The Conversation Breakdowns in the sinoatrial and atrioventricular nodes can cause heart rate problems. Credit: Rob Kreuger, medical illustrator/Wikimedia Commons, CC BY-SA Your heart’s job is to keep your pulse steady to pump blood throughout your body. Sometimes your heart rate is slower when you’re relaxing, and sometimes it’s faster when you’re exercising...
Written by Karen Hovav, MD, FAAP | Reviewed by Katie E. Golden, MD GoodLifeStudio/E+ via Getty Images Key takeaways: When you have a canker sore, it can be painful to eat, drink, or even talk. Thankfully, canker sores are usually temporary and resolve in 1 to 2 weeks. In the meantime, you can adjust what...
Written by Jill Barat, PharmD | Reviewed by Sarah Gupta, MD Key takeaways: If you’ve found yourself tossing and turning at night or waking up in the wee hours unable to go back to sleep, you’re not alone. About 30% of adults deal with insomnia. Natural supplements are a popular treatment option. But is there...
by Wellcome Trust Sanger Institute Experimental design overview. a Two independent sgRNAs and associated HDR variant libraries are designed at the 5′ and 3′ end of each exon. b The sgRNA, together with the HDR template library are transfected into LIG4-KO Cas9-expressing HAP1 cells. HDR utilizes the library as a template for repair of the sgRNA-directed...
by Hong Kong Baptist University Development and characterization of Fe65-engineered exosomes. a Schematic diagram showing the steps involved in the production of engineered Fe65-EXO. Representative b, c immunofluorescence images showing expression of Fe65, d protein level of Fe65 in control- and Fe65 OE- HT22 hippocampus neuron cells. Representative e–g size distribution, h–j, k–m CD63-, and Fe65-positive...
by Sydney E. Smith, The Conversation Credit: Pixabay/CC0 Public Domain When most people hear about electroconvulsive therapy, or ECT, it typically conjures terrifying images of cruel, outdated and pseudo-medical procedures. Formerly known as electroshock therapy, this perception of ECT as dangerous and ineffective has been reinforced in pop culture for decades—think the 1962 novel-turned-Oscar-winning film “One...
by Cleveland Clinic Percentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed at wileyonlinelibrary.com] A Cleveland Clinic study looked at the long-term use of anti-obesity medications and found that only 19% of the study participants continued to use the...
by Kate Irving, The Conversation Credit: Pixabay/CC0 Public Domain Around 36% of people in England with dementia are unaware they have the condition, according to a new report from the Dementia Commission. The report suggests things health and care professionals can do to improve spotting early signs of dementia. But what can you do if you...
by Lori Solomon Personalized colorectal cancer (CRC) screening based on individual life expectancy may increase the value of CRC screening programs, according to a study published online Oct. 27 in the American Journal of Gastroenterology. Po-Hong Liu, M.D., from the University of Texas Southwestern Medical Center in Dallas, and colleagues examined receipt of past-year CRC...
by National Cerebral and Cardiovascular Center Credit: JAMA Network Open/ National Cerebral and Cardiovascular Center A recent study demonstrated the safety of cilostazol in patients with mild cognitive impairment (MCI), but did not demonstrate any efficacy in preventing disease progression. However, after administration of cilostazol, the blood concentrations of the albumin and β-amyloid complex (albumin-Aβ...
