by University of California, San Francisco Graphical abstract. Credit: Neuron (2024). DOI: 10.1016/j.neuron.2024.01.029Scientists at UC San Francisco may have discovered a new way to test for autism by measuring how children’s eyes move when they turn their heads. They found that kids who carry a variant of a gene that is associated with severe autism are...
by Verena Schulz, Helmholtz Association of German Research Centres Central inceptor immunoreactivity is restricted to neurons, including those regulating energy and glucose metabolism. Credit: Nature Metabolism (2024). DOI: 10.1038/s42255-024-00991-3Research targeting the insulin-inhibitory receptor, or inceptor, unveils promising avenues for beta cell protection, offering hope for causal diabetes therapy. A novel study in mice with diet-induced obesity...
by Cactus Communications T cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogramming and how metabolism can drive T cell exhaustion. Credit: Bo Huang from Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical CollegeWhen foreign antigens...
by Salk Institute Human astrocytes (green) extending processes that wrap around the host blood vessel (magenta). Credit: Salk InstituteThe brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain. The other half—roughly 85 billion cells—are non-neuronal cells called glia. The most common...
by American Heart Association Credit: Unsplash/CC0 Public Domain An analysis of 430,000 adults in the U.S. found that using cannabis, most commonly through smoking, eating, or vaporizing it, was significantly associated with a higher risk of heart attack and stroke, even after controlling for tobacco use (combustible cigarettes and other tobacco products) and other cardiovascular risk...
by QIMR Berghofer Credit: Unsplash/CC0 Public DomainAn international research team led by QIMR Berghofer and Peter MacCallum Cancer Center has discovered that people with the hereditary cancer disorder Li Fraumeni syndrome are at greater risk of a much broader spectrum of cancers than previously thought. Li Fraumeni syndrome is a rare but devastating condition, which...
Finasteride, a common drug used to treat hair loss and enlarged prostate, may also help lower cholesterol levels and reduce the risk of heart disease. stefanamer/Getty ImagesA new study has found that finasteride may be able to reduce cholesterol levels.The drug is currently used for male pattern baldness and enlarged prostate.Men taking the drug had...
by Mass General Brigham Credit: Karolina Grabowska from PexelsRheumatoid arthritis impacts approximately 2 million people in the United States and is associated with increased risk of cardiovascular disease. However, assessing cardiovascular risk is difficult in patients with rheumatoid arthritis because standard clinical assessments based on factors like age, cholesterol, and smoking status tend to underestimate cardiovascular...
by Universitat Politècnica de Valènci Monitoring of senolytic intervention with the sulfonic-Cy7Gal probe during natural aging. a Schedule of the senolytic treatment and its monitoring in C57BL/6 mice. 15-m mice received the senolytic drugs D + Q or the vehicle for 5 weeks and, 13 days after senolysis (DAS), the overall β-Gal activity was assessed with sulfonic-Cy7Gal...
by The Hospital for Sick Children Functional characteristics of rare tandem repeat expansions. a Burden of rare tandem repeat expansions in different genomic features in individuals with CMP compared to controls. Credit: eBioMedicine (2024). DOI: 10.1016/j.ebiom.2024.105027In the first study to use whole genome sequencing to examine tandem repeat expansions in heart conditions, scientists at The Hospital...
