Ted Bosworth West Palm Beach, Florida — In an interim analysis of an extension study, intrathecal injection of autologous bone marrow–derived mesenchymal stem cells (MSCs) has been associated with favorable effects on both symptoms and biomarkers in patients with progressive multiple sclerosis (MS), new data presented as a late breaker at the annual meeting held...
Month: <span>March 2024</span>
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A noninvasive treatment for “chemo brain”
Stimulating gamma brain waves may protect cancer patients from memory impairment and other cognitive effects of chemotherapy. Anne Trafton | MIT News Patients undergoing chemotherapy often experience cognitive effects such as memory impairment and difficulty concentrating — a condition commonly known as “chemo brain.” MIT researchers have now shown that a noninvasive treatment that stimulates gamma frequency...
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Researchers Uncover How Gene Traits Are Passed On
Understanding how this coupled mechanism could lead to new treatments for cancer and other epigenetic diseases. the University of Hong Kong Credit: iStock. A research team led by Professor Yuanliang ZHAI at the School of Biological Sciences, The University of Hong Kong (HKU) collaborating with Professor Ning GAO and Professor Qing LI from Peking University...
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Genetic “Switch” Controlling Anxiety Discovered
A genetic “switch” has been identified that plays a role in controlling anxiety levels, which could provide a new anxiety drug target. University of Aberdeen Credit: Liza Summer/ Pexels New research from the University of Aberdeen has identified an area of DNA in the human genome that plays a role in controlling anxiety. In the...
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Myocarditis game-changer: We’ve blamed the wrong culprit
By Paul McClure Findings from a new study have challenged traditional assumptions about what causes myocarditisAI-generated by DALL-E Inflammation resulting from a viral infection has traditionally been thought to cause acute myocarditis, which can lead to fatal heart arrhythmias in otherwise healthy young adults. Now, a new study has shown for the first time that...
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‘Double life’ of key immune protein reveals new strategies for treating cancer and autoimmune diseases
by NYU Langone Health Credit: CC0 Public DomainInsights into the workings of an immune cell surface receptor, called PD-1, reveal how treatments that restrict its action can potentially be strengthened to improve their anticancer effect, a new study shows. The same findings also support experimental treatment strategies for autoimmune diseases, in which the immune system...
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Researchers develop shortcut to generate brain stem cells for age-related disease research
by The University of Hong Kong Credit: Nucleic Acids Research (2023). DOI: 10.1093/nar/gkad597A research team from the School of Biomedical Sciences, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), has achieved a breakthrough in stem cell research, offering tools that can be used for patients who require highly personalized care. The team...
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Frexalimab Promising for Relapsing Multiple Sclerosis
Megan Brooks Frexalimab (Sanofi), a novel, investigational second-generation inhibitor of the CD40 ligand, significantly reduced disease activity in relapsing multiple sclerosis (MS) and was well tolerated in a phase 2 study. At week 12, there was an 89% reduction in new gadolinium (Gd)-enhancing T1 brain lesions — a standard measure of active inflammation in MS...
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Growth cone in migrating neurons involved in promoting neuronal migration and regeneration in brain injury, study shows
by Nagoya City University Collective time-lapse images of a migrating neuron (bottom) and an elongating axon (top) from super-resolution microscopy. Growth cones at the tips of the neurons are extended while the cell body migrates and the axon elongates. Credit: Nagoya City University Gradualte School of Medical SciencesThe structure and functions of the tip of...
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Why is the brain so prone to inflammation?
by Sarah C.P. Williams, Columbia University Irving Medical Center Keeping neuroinflammation in check. Normal neurons (top panel) produce a small amount of double-stranded DNA (green) that keeps inflammation at a low level and ready to fight incoming viruses. But if neurons accumulate extremely high levels of dsRNA, as seen in ADAR1 knockout neurons (lower panel),...