by Impact Journals LLC Correlation between epigenetic clocks and immune cell types. The size of the dots is proportional to the correlation value, being blue a positive correlation and red a negative correlation. Credit: Aging (2024). DOI: 10.18632/aging.205581A new research paper titled “Exploring the effects of dasatinib, quercetin, and fisetin on DNA methylation clocks: a...
Month: <span>March 2024</span>
Post
Factors associated with age-related hearing loss differ between males and females, finds study
by Public Library of Science The study suggests that factors associated with age-related hearing loss differ between males and females. Credit: Mark Paton, Unsplash, CC0 (creativecommons.org/publicdomain/zero/1.0/)Certain factors associated with developing age-related hearing loss differ by sex, including weight, smoking behavior, and hormone exposure, according to a study published in the open-access journal PLOS ONE by Dong...
Post
The journey to relieve endometriosis pain
by Pennsylvania State University Credit: Pixabay/CC0 Public DomainSome women spend as much as a month of every year in so much pain they can do little more than endure it. “We’re talking about pain that’s beyond ‘I took two ibuprofen and went to work,'” said Dr. Kristin Riley. “We’re talking about pain that keeps people from...
Post
Tacrolimus microemulsion has good efficacy, safety for scalp psoriasis
by Elana Gotkine For scalp psoriasis, 0.1 percent tacrolimus microemulsion has good efficacy and safety, according to a study published online Feb. 12 in Dermatology and Therapy. Andreas Pinter, M.D., from the University Hospital Frankfurt in Germany, and colleagues conducted a multicenter, double-blind, vehicle-controlled phase 3 trial to examine the efficacy and safety of 0.1...
Post
Endolymphatic hydrops, nystagmus can help ID subgroups of Meniere disease
by Lori Solomon Subgroups of Meniere disease (MD) can be made based on the presence or absence of endolymphatic hydrops (EH) and nystagmus, according to a study published online Jan. 10 in Frontiers in Neurology. Yuya Ueno, from the Osaka University Graduate School of Medicine in Japan, and colleagues used nystagmus videos and contrast-enhanced magnetic...
Post
New Microscopy Tool Captures Data From 1 Million Neurons Simultaneously
Light-beads microscopy has enabled a 100-fold increase in the number of neurons that can be simultaneously recorded. The mammalian brain is a web of densely interconnected neurons, yet one of the mysteries in neuroscience is how tools that capture relatively few components of brain activity have allowed scientists to predict behavior in mice. It is...
Post
AI Outscores Pathologists Predicting Lung Cancer Spread
AI algorithms have been used to assess whether lung cancer will spread, and they outperformed clinicians.Original story from California Institute of Technology Lung Cancer Metastasis. Credit: Scott Wilkinson, Adam Marcus/ National Cancer InstituteFor decades, scientists and pathologists have tried, without much success, to come up with a way to determine which individual lung cancer patients...
Post
Common Biological Basis Identified in Schizophrenia and Aging
Tightly synchronized genetic changes in two types of brain cells may underlie cognitive impairment in both conditions. Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have uncovered a strikingly similar suite of changes in gene activity in brain tissue from people with schizophrenia and from older adults. These...
Post
ER visits for infant, child melatonin poisonings are soaring
by Ernie Mundell As more Americans pop over-the-counter melatonin to help them sleep, their young children are increasingly showing up in ERs after accidentally ingesting the supplements. A new report of data from 2012 through 2021 finds a 420% rise in such cases during that time, along with a 530% increase in calls to poison...
Post
AAAAI: Nasal delivery of epinephrine safe, effective for anaphylaxis
by Lori Solomon Nasal powder formulations of epinephrine are effective and show superior stability to EpiPens, according to a study presented at the annual meeting of the American Academy of Allergy, Asthma & Immunology, held from Feb. 23 to 26 in Washington, D.C. Martin Jönsson, from Orexo AB in Uppsala, Sweden, and colleagues evaluated the...