by University of Manitoba Non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) improves the colitis-related disease activity index (DAI) and macroscopic score. Credit: Bioelectronic Medicine (2024). DOI: 10.1186/s42234-024-00162-5 A simple, non-invasive treatment focused on the ears could one day provide relief for people with ulcerative colitis, a UM research study has found. The study, “Exploring the efficacy of transcutaneous...
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Enhanced dual-mode imaging: New transducer delivers ultrasound and photoacoustic imaging simultaneously
by Pohang University of Science and Technology A transparent ultrasound transducer-based photoacoustic-ultrasound fusion probe, along with images of a rat’s rectum and a pig’s esophagus. Credit: POSTECH A research team has developed the world’s first high-performance photoacoustic endoscopy based on a transparent ultrasonic transducer. Their findings were recently published in the journal Science Advances. Endoscopic ultrasound is widely used...
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Researchers find previously unknown links between microbial bile acids and the risk of colon cancer
by University of Wisconsin-Madison From left, Ting Fu, assistant professor in the UW–Madison School of Pharmacy, postdoctoral researcher Xingchen Dong, and graduate student Fei Sun prepare samples for examination. Credit: Sally Griffith-Oh / UW–Madison Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats....
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Horseshoe crab and tarantula-derived peptides may provide key to beating drug-resistant melanoma
by Queensland University of Technology Credit: Pharmacological Research (2024). DOI: 10.1016/j.phrs.2024.107298 Antimicrobial peptides derived from a crab and a spider may provide the pathway to overcoming drug resistance in advanced melanoma. QUT researchers based at Brisbane’s Translational Research Institute (TRI) have modified the peptides from the Brazilian tarantula and the Japanese horseshoe crab and found they can kill...
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Breathing coordinates brain rhythms for memory consolidation during sleep
by Northwestern University Corresponding author Andrew Sheriff looks at a computer monitor in a lab. Credit: Northwestern University Just as a conductor coordinates different instruments in an orchestra to produce a symphony, breathing coordinates hippocampal brain waves to strengthen memory while we sleep, reports a new Northwestern Medicine study. This is the first time breathing rhythms...
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Exploring the heterogeneity of metabolic dysfunction-associated steatotic liver disease
by Deutsches Zentrum fuer Diabetesforschung DZD Credit: Norbert Stefan, IDM / DZD About 70% of obese people have metabolic dysfunction-associated steatotic liver disease (MASLD). However, MASLD is also found in lean people. Paradoxically, some effective pharmacological approaches to improve liver health in people with MASLD are associated with no change in body weight or even...
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Paper-based biosensor offers pain-free diabetes monitoring via sweat
by Chris Kocher, Binghamton University A new paper-based biosensor system uses bacterial spores that germinate in response to glucose in potassium-rich bodily fluids, such as sweat. Credit: Binghamton University Millions of people with diabetes track their glucose levels daily using finger-stick devices that draw and analyze their blood. But what if they could monitor it with...
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Diabetes drug linked to increased risk of severe eye condition
by Nana Olejank Hansen, University of Southern Denmark Credit: CC0 Public Domain Two independent studies from the University of Southern Denmark (SDU) show that patients with type 2 diabetes who are treated with the drug Ozempic have an increased risk of developing damage to the optic nerve of the eye, which can lead to severe and...
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Drugs to Target Lp(a): What’s Coming
Michelle L. O’Donoghue, MD, MPH; Stephen J. Nicholls, MBBS, PhD DISCLOSURES | December 13, 2024 Michelle L. O’Donoghue, MD, MPH: Hi. This is Dr Michelle O’Donoghue, reporting for Medscape. I’m here at the American Heart Association Scientific Sessions. It’s a very exciting meeting, but one of the interesting topics that we’re going to be talking about is lipoprotein(a) [Lp(a)] ....
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Technosphere insulin + insulin degludec noninferior to usual care in T1DM
by Elana Gotkine For adults with type 1 diabetes, a regimen of inhaled Technosphere insulin (TI) plus insulin degludec is noninferior to usual care for glycemic control, according to a study published online Dec. 6 in Diabetes Care. Irl B. Hirsch, M.D., from the University of Washington in Seattle, and colleagues examined a regimen of TI...