Molding complex tissues using galliumPeer-Reviewed Publication Boston University When it comes to the human body, form and function work together. The shape and structure of our hands enable us to hold and manipulate things. Tiny air sacs in our lungs called alveoli allow for air exchange and help us breath in and out. And tree-like...
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Stanford scientists transform ubiquitous skin bacterium into a topical vaccine
Peer-Reviewed Publication Stanford Medicine Imagine a world in which a vaccine is a cream you rub onto your skin instead of a needle a health care worker pushes into your one of your muscles. Even better, it’s entirely pain-free and not followed by fever, swelling, redness or a sore arm. No standing in a long...
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Scientists discover new receptor for nerve growth factor—a promising target for treating pain
by New York University Nerve growth factor receptor TrkA (in green) and co-receptor NRP1 (in purple) are coexpressed in the same nerve cells in mice. Credit: Bunnett Lab Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does...
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Understanding how the immune system switches between rest and action
Scientists at Gladstone and UCSF discover how one protein controls the behavior of immune cells, with potential applications for treating cancer and autoimmune conditionsPeer-Reviewed Publication Gladstone Institutes image: Scientists at Gladstone and UC San Francisco—including Maya Arce, seen here—discover how one protein controls the behavior of immune cells, with potential applications for treating cancer and...
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Nature Biotechnology | Generative chemistry enables Insilico to develop gut-restricted PhD inhibitors promising for intestinal mucosal barrier repair and immunomodulation
Peer-Reviewed Publication InSilico Medicine image: The study, published in Nature Biotechnology, highlights the role of Chemistry42 and its submodules in supporting drug candidate design and optimization. The research underscores the potential of advanced AI technologies to accelerate the fulfillment of urgent clinical needs.view more Credit: Insilico Medicine Inflammatory bowel disease (IBD), consisting primarily of ulcerative colitis and...
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New treatment may delay cancer in high-risk myeloma
by Kelley Luckstein, Mayo Clinic Credit: Mayo Clinic A new treatment is showing promise for people with high-risk smoldering multiple myeloma (SMM). This precancerous condition can progress to active multiple myeloma, a type of blood cancer. High-risk SMM carries a higher likelihood of progression. Results from a phase 3 clinical trial, published in the New England Journal of Medicine and...
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Research uncovers key bariatric surgery complication cause
by Maria Fernanda Ziegler, FAPESP Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI180157 Postprandial hypoglycemia is one of the main complications of bariatric surgery and can affect up to 30% of patients. Unlike ordinary hypoglycemia, in which low blood sugar is usually associated with little food, postprandial hypoglycemia occurs after meals and causes symptoms such as sweating, tremors,...
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Cardiorespiratory fitness linked to preservation of cognitive abilities in older age
by British Medical Journal Credit: Pixabay/CC0 Public Domain Higher cardiorespiratory fitness in older age is linked to the preservation of several core aspects of cognitive ability that are vulnerable to age-related decline, finds research published online in the British Journal of Sports Medicine. And this association holds true irrespective of key risk factors for cognitive decline: age and...
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Celiac disease linked to higher risk for developing alopecia areata
by Lori Solomon Celiac disease is associated with an increased risk for developing alopecia areata, according to a letter to the editor published online Nov. 21 in the Journal of the American Academy of Dermatology. Rashwan Alameddine, from the Texas A&M University College Station in Bryan, and colleagues investigated the potential association between celiac disease and the prevalence of alopecia areata....
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Scientists estimate around 1 in 5 of the world’s under 50s living with genital herpes
by British Medical Journal Credit: Pixabay/CC0 Public Domain The latest global estimates suggest 846 million people are living with genital herpes infection. The findings are published online in the journal Sexually Transmitted Infections. And more than 200 million 15–49 year olds probably had at least one symptomatic outbreak of the infection in 2020, the latest year for which figures are...