By Maya Goldman Illustration: Shoshana Gordon/Axios Some supplement companies are vying to get into the booming GLP-1 space, adding a new layer of complexity to accessing anti-obesity treatments.Why it matters: GLP-1s are expensive and in short supply. Supplements promoted with similar claims may be easier to come by, but experts warn they don’t have to meet...
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Why the genetic-testing revolution left some people behind — and what to do about it
Thirty years after the sequencing of the BRCA1 cancer-associated gene, access to genetic tests and awareness about its risks are still too limited. Evolutionary geneticist Mary-Claire King did not anticipate the impact of her discovery.Credit: Rina Castelnuovo/New York Times/Redux/eyevine When Mary-Claire King embarked on a painstaking 17-year-long hunt for a gene linked to breast cancer, she had...
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X-chromosome study reveals hidden genetic links to Alzheimer’s disease
By Hugo Francisco de SouzaReviewed by Susha Cheriyedath, M.Sc.Dec 9 2024 Despite decades of research, the X-chromosome’s impact on Alzheimer’s was largely ignored until now. Explore how seven newly discovered genetic loci could revolutionize our understanding of the disease. Study: X‐chromosome-wide association study for Alzheimer’s disease. Image Credit: nobeastsofierce / Shutterstock Conventional investigations of the genetic contributors to Alzheimer’s disease...
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BEST TIME FOR A COVID BOOSTER ISN’T THE SAME FOR EVERYONE
DECEMBER 10TH, 2024POSTED BY YALE A nurse prepares a dose of a Covid-19 vaccine for Margaret Keenan, 91, prior to her receiving a spring Covid-19 booster shot at University Hospital Coventry on April 22, 2022 in Coventry, England. (Credit: Jacob King – WPA Pool / Getty Images) SHARE THIS ARTICLE You are free to share this article under...
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1 GENE MAY PUT YOU AT HIGHER RISK OF BREAST CANCER’S SPREAD
DECEMBER 10TH, 2024POSTED BY KATHERINE FENZ-ROCKEFELLER (Credit: Getty Images) SHARE THIS ARTICLE You are free to share this article under the Attribution 4.0 International license. TAGS UNIVERSITY ROCKEFELLER UNIVERSITY Researchers have discovered a genetic predisposition that increases the risk of breast cancer metastasis. Ninety percent of cancer deaths are due to the spread of cancer, not complications from the original...
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Identifying a proliferating repairman for tissue in damaged lungs
Penn Vet and Penn Medicine researchers found that endothelial cells lining the veins in lungs contribute to repair of blood vessels after lung injuryPeer-Reviewed Publication University of Pennsylvania Veins in the lungs, or pulmonary veins, play a critical role not only in lung functioning but also in maintaining sufficient oxygen in tissue throughout the body....
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Brain volume changes seen in opioid users
Peer-Reviewed Publication Radiological Society of North America image: Tensor-based morphometry (TBM) analysis of T1-weighted MRI scans shows a comparison of brain volumes in participants with opioid use disorder (OUD) and healthy control participants. Widespread volume differences are observed between participants with OUD and healthy controls when accounting for total brain volume. Specifically, the bilateral thalamus,...
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Portable MRI shows promise for expanding brain imaging for Alzheimer’s disease
By leveraging machine learning tools, Mass General Brigham researchers measured markers of Alzheimer’s disease on portable MRI with accuracy matching that of standard MRIPeer-Reviewed Publication Massachusetts General Hospital Globally, approximately 139 million people are expected to have Alzheimer’s disease (AD) by 2050. Magnetic resonance imaging (MRI) is an important tool for identifying changes in brain...
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American Psychiatric Association publishes updated practice guideline on the treatment of borderline personality disorder
Reports and Proceedings American Psychiatric Association WASHINGTON, D.C., Dec. 9, 2024—The American Psychiatric Association (APA) today published an updated Practice Guideline for Treatment of Patients with Borderline Personality Disorder. The guideline provides recommendations on evidence-based assessment, treatment planning, and psychosocial interventions and pharmacotherapy treatments. Borderline personality disorder is classified among the personality disorders and affects 1.4%-2.7%...
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New gene therapy reverses heart failure in large animal model
by University of Utah Health Sciences Fluorescent microscope image of previously failing heart cells that have received cBIN1 gene therapy. Green is a label that indicates the location of cell membranes. The green stripes indicate that the microscopic architecture of heart cells is closer to normal. Credit: Hong lab A new gene therapy can reverse the...