Month: <span>December 2024</span>

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A string of pearls: Study challenges long-held beliefs about shape, functioning of nerve cells

Peer-Reviewed Publication Marine Biological Laboratory image:  Electron microscope image of a cryo-preserved axon shows details of its pearls-on-a-string nanomorphology. Credit: Quan Gan and Mitsuo Sugaview more  Credit: Quan Gan and Mitsuo Suga WOODS HOLE, Mass. — In a provocative new study, scientists challenge a fundamental tenet in neuroscience about the shape of axons — the long,...

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Discovering the mechanism behind brain’s inhibition network: From vision to action control

A new study reveals how key brain regions regulate inhibitory actions, paving the way for impulse control disorder treatmentPeer-Reviewed Publication Juntendo University Research Promotion Center image:  Advanced brain imaging reveals how key regions work together to control impulses, paving the way for new treatments for impulsive disordersview more  Credit: Dr. Takahiro Osada from Juntendo University, Japan...

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Evaluating long-term survival and cardiac efficacy of a gene therapy for Duchenne muscular dystrophy

by Mary Ann Liebert, Inc Fibrotic remodeling in skeletal muscle and heart of DMDMDX rats and impact of delandistrogene moxeparvovec treatment. A recent study published in the journal Human Gene Therapy evaluated the long-term survival and cardiac efficacy of the gene therapy delandistrogene moxeparvovec in a rat model of Duchenne muscular dystrophy (DMD). Delandistrogene moxeparvovec uses an adeno-associated viral (AAV) vector...

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Research shows dupilumab effective in treatment of children with atopic dermatitis

by National Jewish Health Credit: CC0 Public Domain Research at National Jewish Health and other institutions has shown that the biologic dupilumab improves signs and symptoms of moderate-to-severe atopic dermatitis (eczema) in young children whether or not they have another inflammatory condition, such as asthma, allergic rhinitis or food allergies. Dupilumab had previously been shown to...

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MDMA-assisted therapy could improve neurorehabilitation of injured service members beyond PTSD

by University of California, Los Angeles Credit: Pixabay/CC0 Public Domain A UCLA Health analysis of MDMA-assisted therapy research suggests that the drug could improve outcomes of treatment of a wider range of trauma-related conditions experienced by military personnel beyond the current focus on post-traumatic stress disorder (PTSD) by increasing a collaborative and trusting relationship between a...

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Women pay for AI to boost mammogram findings

by Radiological Society of North America AI enhanced screening mammography. Credit: Radiological Society of North America (RSNA) and DeepHealth More than a third of women across 10 health care practices chose to enroll in a self-pay, artificial intelligence (AI)-enhanced breast cancer screening program, and the women who enrolled were 21% more likely to have cancer detected,...

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Advice from a cardiologist: Cardiac arrest vs. heart attacks

by Mayo Clinic News Network Credit: Pixabay/CC0 Public Domain Sudden cardiac arrest may occur in various conditions when someone, while active (playing basketball or walking with friends), collapses and passes out. Their blood pressure drops, and often their heart stops. This may be caused by a lethal arrhythmia, which is when the heart beats abnormally...

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How home fragrances can impact indoor air quality, and your health

by Asit Kumar Mishra, Marie Coggins, The Conversation Credit: Pixabay/CC0 Public Domain During winter, many of us use fragrances to help create a cozy, festive feeling in our homes. From gingerbread, cinnamon and pine scented candles to frankincense and myrrh diffusers, it’s becoming increasingly popular to use scents to evoke the Christmas spirit. The UK home fragrance...

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Predictive model identifies at-risk patients who may need stomach cancer screening

by Cleveland Clinic Credit: Pixabay/CC0 Public Domain Cleveland Clinic developed a predictive model to identify patients at risk of developing gastric (stomach) cancer who may benefit from stomach cancer screening. The model is designed to identify who might need regular upper endoscopies to screen for stomach cancer. Although U.S. patients get routinely screened for other diseases,...

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Sex differences in neuron protection could reveal Alzheimer’s target

by Jim Schnabel, Cornell University Biological sex modulates responses to demyelination with age or disease pathology through Tlr7. Credit: Science (2024). DOI: 10.1126/science.adk7844 Inhibiting TLR7, an immune signaling protein, may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer’s disease and ordinary aging, suggests a study led by researchers at Weill Cornell Medicine....