People may only be able to breathe through one nostril due to congestion, allergies, a blockage, or natural changes in the nasal cycle. This is not uncommon and may get better on its own. The nasal cycle refers to the way tissue inside the nose regulates the size of the air passages, opening or narrowing...
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Vertex drug for cystic fibrosis wins approval
The FDA just approved Alyftrek, a once-daily medicine for a small slice of cystic fibrosis patients that carry certain mutations, including F508del. It’s a triple combination CFTR modulator that works across 31 other mutations, and outperformed Trikafta — another popular Vertex drug for cystic fibrosis — in its ability to reduce sweat chloride levels. This is the...
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FDA approves generic in same class as Ozempic for diabetes. Could it ease shortage, price?
Karen Weintraub USA TODAY 0:04 1:50 In a move that could eventually make weight loss drugs cheaper and easier to access, the Food and Drug Administration Monday approved a second generic in the category of medications known as GLP-1s. The drugs were first approved to treat type 2 diabetes – and that’s what the FDA said daily injections of liraglutide...
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Neuroscience leader reveals oxytocin’s crucial role beyond the ‘love hormone’ label
Distinguished professor Inga Neumann discusses groundbreaking social behavior research in exclusive Genomic Press InterviewReports and Proceedings Genomic Press image: Inga D. Neumann working at the Tacugama Chimpanzee Sanctuary in Sierra Leone, preparing enrichment material for chimpanzee orphans.view more Credit: Inga D. Neumann REGENSBURG, Bavaria, Germany, 24 December 2024 – In a comprehensive Genomic Press Interview, Professor Inga...
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TNF inhibitors prevent complications in kids with Crohn’s disease: Study recommends them as first-line therapies
by Sam Page, University of Michigan Credit: Kindel Media from Pexels Early treatment of pediatric Crohn’s disease with anti-tumor necrosis factor medications can substantially reduce the risk of perianal fistulas, a particularly debilitating complication of Crohn’s disease. Michigan Medicine researchers confirmed this finding using prospective data. The resulting paper, “Early tumour necrosis factor antagonist treatment prevents perianal fistula development...
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Engineering a smile: Stem cell–based conduits restore facial nerve function in animal study
by National Institutes of Health Facial nerve injuries are often treated with tissue taken from a patient’s body, called autografts. Alternatively, researchers are developing engineered conduits which could potentially be more accessible. Credit: NIBIB. Created with BioRender.com A gesture as simple as a smile can often convey what words cannot. This is part of why nonverbal...
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Engineered T cells could help patients overcome resistance to CAR T cell therapy
by City of Hope National Medical Center Engineering a leucine zipper-based cell-sorting system. Credit: Nature Biomedical Engineering (2024). DOI: 10.1038/s41551-024-01287-3 Physician-researchers with City of Hope have developed a way to add features to T cells to help them overcome mechanisms of chimeric antigen receptor (CAR) T cell therapy resistance. Their new system is outlined in a paper published in Nature Biomedical...
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Reprogramming cells for heart repair: New method transforms ordinary fibroblasts into mature cardiomyocytes
by Korea University College of Medicine This diagram illustrates how the combination of fibroblast growth factor 4 and ascorbic acid activates the JAK2–STAT3 signaling pathway, promoting the maturation of induced cardiomyocytes (iCMs). This approach effectively reprograms fibroblasts into cardiomyocytes with improved structure and function, offering exciting possibilities for regenerative medicine. Credit: The authors Cardiovascular disease...
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Here’s why you might – or might not – want to add sugar to your coffee
By Michael Franco December 24, 2024 A new study shows that adding sugar to coffee can have a surprising effect on circadian rhythms Depositphotos View 1 Images A new study turned up a surprising effect of having caffeine with a sweetener. For some java drinkers, it could be a way to get more out of the...