By Vijay Kumar MalesuJan 24 2024Reviewed by Danielle Ellis, B.Sc. In a recent study published in JAMA Neurology a group of researchers determined the utility of a novel and commercially available immunoassay for plasma phosphorylated tau 217 (p-tau217) to detect Alzheimer’s Disease (AD) pathology and evaluate reference ranges for abnormal amyloid β (Aβ) and longitudinal...
Year: <span>2024</span>
Persistent presence of SARS-CoV-2 RNA found in long COVID patients
By Dr. Sanchari Sinha Dutta, Ph.D.Jan 23 2024Reviewed by Benedette Cuffari, M.Sc. In a recent study published on the medRxiv* preprint server, researchers conducted blood digital transcriptomics to determine the persistence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA) in patients living with long-term consequences of coronavirus disease 2019 (COVID-19). Study: Blood...
No cervical cancer cases in HPV-vaccinated women
The HPV immunisation programme began in 2008 in ScotlandA new study has found that no cases of cervical cancer have been detected in young women who have been fully-vaccinated as part of the HPV immunisation programme. The Public Health Scotland (PHS) research said the HPV (human papillomavirus virus) vaccine was “highly effective” in preventing the...
Few patients successfully treat their type 2 diabetes through weight loss, study suggests
by Public Library of Science Weight loss and diabetes remission. Credit: Diana Polekhina, Unsplash (CC0, creativecommons.org/publicdomain/zero/1.0/)A new study finds that very few patients diagnosed with type 2 diabetes are able to achieve normal blood glucose levels through weight loss alone. A team led by Andrea Luk of the Chinese University of Hong Kong, report these findings...
Why are measles cases popping up across the United States? Here’s what to know about the highly contagious virus
By Amanda Musa and Carma Hassan, CNN About 92% of US children have been vaccinated against measles, mumps and rubella by age 2, according to the CDC – below the federal target of 95%.George Frey/Getty ImagesCNNNearly a dozen cases of measles have been reported in Pennsylvania, Virginia and Georgia in recent weeks, according to local...
Financial stress linked to worse biological health, finds study
by University College London Credit: Unsplash/CC0 Public DomainPeople who experience stressful life events or circumstances are more likely to have worse biological health, as indicated by biomarkers involved in the interaction between our immune, nervous and endocrine systems, according to a new study by UCL researchers. The study, published in the journal Brain, Behavior and Immunity,...
How unexpected weight loss can sometimes be an indicator of cancer
In a new study, researchers report that health professionals who lost weight without starting a diet or exercise plan within the previous two years had a significantly higher risk of developing cancer within the following year.Upper gastrointestinal tract, hematologic, colorectal, and lung cancers were more common in people with rapid unexpected weight loss.Experts say people...
Detecting bowel cancer without a stool test
by South Australian Health and Medical Research Institute (SAHMRI) Schematic of orally-delivered EcN probiotic engineered to lyse and produce immunotherapeutic proteins in situ (top) and schematic of dosing regimen (bottom). Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-44776-4An international team of researchers from Adelaide and the United States has opened the door to non-stool-based bowel cancer detection...
Chemotherapy becomes more efficient when senescent cells are eliminated by immunotherapy, shows study
by Institute for Research in Biomedicine (IRB Barcelona) Senescent human melanoma tumor cells. In brown, the PD-L2 protein acts as a protective shield and prevents the action of the immune system. Credit: IRB BarcelonaCancer treatments, including chemotherapy, in addition to killing a large number of tumor cells, also result in the generation of senescent tumor cells...
Protein TDP-43 keeps genetic zombies at bay: New insights into neurodegenerative disease mechanisms
by Quinn Eastman, Emory University Graphical abstract. Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2023.113662A new Cell Reports paper from Bing Yao’s lab in Emory’s Department of Human Genetics provides insights into mechanisms underlying several neurodegenerative diseases, such as ALS (amyotrophic lateral sclerosis) and Alzheimer’s. It can be summarized in one line: TDP-43 keeps genetic zombies at bay....