by Michelle Marchante, Miami Herald Credit: Pixabay/CC0 Public DomainTraveling by plane isn’t always easy on the body. And neither is space travel. Astronauts often experience atrophy, the loss of bone and muscle, during their months living in space’s zero gravity. People on Earth also tend to see their bones and muscles weaken as they age,...
by Anne Trafton, Massachusetts Institute of Technology The cysts that appear in ADPKD cause kidneys to enlarge until they no longer function properly (center image). At the right is a kidney following treatment with the new compound, which has shrunk to a size similar to that of an undiseased kidney (left). Credit: Massachusetts Institute of TechnologyAutosomal...
by Daniel Meierhans, ETH Zurich The DEGs we identified upon 2 h, and 18 h of DEX treatments in A549 cells align with the other existing RNAseq and ChIP-seq datasets. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-44031-2Stress isn’t merely an oppressive feeling we experience when we’re overwhelmed; it’s the body’s natural reaction to acute or persistent strain. This stress...
by Anne Grimm, Leipzig University Credit: CC0 Public DomainWhen people develop myelodysplastic neoplasms (MDS), the healthy maturation of blood cells is impaired. Severe forms, known as higher-risk MDS, are characterized by rapid progression, severe symptoms and often a transition to acute leukemia. Patients for whom potentially curative or intensive treatments, such as stem cell transplantation or...
by Brandon Chase, Massachusetts General Hospital Credit: Pixabay/CC0 Public DomainThe tau protein accumulates in abnormal shapes in the brains of individuals with Alzheimer’s disease (AD), but the early steps of tau misfolding and aggregation are unknown. A team led by investigators at Massachusetts General Hospital (MGH) and Boston Children’s Hospital, recently used advanced proteomics methods to...
Overall cancer mortality in the United States has continued to decline, with more than 4 million cancer deaths averted since 1991, according to the 2024 American Cancer Society (ACS) annual report on cancer trends. The “good news is that we are continuing to see a decline in cancer mortality,” which follows the steady decline we’ve...
Research identifies protein responsible for increasing inflammation and oxidative stressPeer-Reviewed Publication ANGLIA RUSKIN UNIVERSITY A new study has identified a protein that nicotine-free vape fluid increases in the lung, causing damage including oxidative stress, inflammation and breakdown of the blood vessels. The research, published in the journal Microvascular Research demonstrates a range of damaging pathways...
by Diabetologia Credit: Ketut Subiyanto from PexelsWhile several trials have shown that substantial weight loss using diet and lifestyle can reverse type 2 diabetes, new research published in Diabetologia is among the first to show the subsequent impact of remission on cardiovascular outcomes. The study is by Professor Edward Gregg, Head of the School of Population...
by Hackensack Meridian Health Deletion of Tle3 promotes the formation of TCM cells as manifested at the single-cell level. Credit: Nature Immunology (2024). DOI: 10.1038/s41590-023-01720-wThe Xue Lab at the Hackensack Meridian Center for Discovery and Innovation (CDI) has made another breakthrough in better understanding and potentially modulating the immune system to fight diseases. The insights...
Marygrace Taylor It’s no surprise that hair loss becomes more common as we age. Most of the time, there are multiple factors responsible for thinning strands. And that includes falling short on certain key nutrients. But which vitamin deficiency causes hair loss, and how can you get growth back on track? “Certain restrictive diets may...
