Pauline Anderson Transcranial alternating current stimulation (tACS), a noninvasive technique that uses low-intensity electrical currents to modulate brain activity, is an effective intervention for treating chronic insomnia, especially in older people, results of a relatively large study suggested. METHODOLOGY:The double-blind study included 124 adults with chronic insomnia (difficulty falling asleep or maintaining sleep and early...
Year: <span>2024</span>
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New vaccine design uses immunity against influenza to offer faster protection against emerging pathogens
by Iqbal Pittalwala, University of California – Riverside Credit: CC0 Public DomainAfter COVID vaccination, it usually takes weeks for our bodies to develop protective antibody responses. Imagine, however, a vaccine that speeds up the production of antibodies against SARS-CoV-2, the virus that spreads COVID-19. A research team led by Rong Hai, an associate professor of microbiology...
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FDA approves exagamglogene autotemcel to treat beta-thalassemia
by Physician’s Briefing Staff After approving Casgevy (exagamglogene autotemcel) in December to treat sickle cell disease, the U.S. Food and Drug Administration announced Tuesday that the therapy has now been approved to treat patients older than 12 years with transfusion-dependent beta-thalassemia. Casgevy is the first CRISPR-based medicine, where gene editing is used to develop the...
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Effects of resveratrol on circadian clock gene expression in young and older human cells
by Impact Journals LLC Resveratrol increases in vitro rhythmic gene mRNA expression of core clock components in human adipose-derived progenitor cells (APCs) from older participants. Credit: Aging (2024). DOI: 10.18632/aging.205292A new research paper was published on the cover of Aging titled, “Effects of resveratrol on in vitro circadian clock gene expression in young and older...
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New study reveals significant reduction in lumbar spine reoperation with chiropractic spinal manipulation
by University Hospitals Cleveland Medical Center Study design. The vertical arrow represents the index date of enrollment. Windows to the left of this arrow represent preceding time windows over a span of days [#,#], while windows on the right indicate events following the index date of enrollment. The “∞” indicates that the time window reaches as...
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Study shows a single session of aerobic exercise improves blood pressure in rheumatoid arthritis patients
by FAPESP 1: Summary of the experimental sessions. The exercise (upper panel) and control sessions (lower panel) were performed in different days and the order of the experiments was randomized. Both sessions were composed by pre- and post-interventions of blood pressure (BP) and heart rate (HR) at rest and in response to the Stroop Color and...
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Study discovers 103 genes that cause inherited diseases when mutated can also increase cancer risk
by The Spanish National Cancer Research Centre Systematic analysis of the enrichment of rare pathogenic variants in cases compared to control samples. a Proposed hypothesis that rare pathogenic variants in Mendelian disease-associated genes (OMIM genes) increase the risk of cancer. b Overview of the case–control analysis. Principal components analysis (PCA) using common variants was performed to...
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Research team develops contact lenses to diagnose glaucoma
by Northumbria University Photographs of subjects (a) wearing a Type-B contact lens, (b) wearing a Type-D contact lens, (c) wearing a contact lens, an antenna and carrying a readout unit. Credit: Contact Lens and Anterior Eye (2023). DOI: 10.1016/j.clae.2023.102102Glaucoma effects around 70 million people worldwide and can cause irreversible loss of vision if not treated—but around...
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Malnutrition often seen in patients treated for inflammatory bowel disease
by Lori Solomon Some patients seen in an inflammatory bowel disease (IBD) clinic screen positive for malnutrition, according to a research letter published online Nov. 20 in Gastro Hep Advances. Aaron C. Viser, from the University of North Carolina at Chapel Hill, and colleagues used data from a multidisciplinary IBD clinic (June 7 to July...
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Large study finds COVID-19 vaccine reduces long COVID in children
by Children’s Hospital of Philadelphia A medical assistant prepares a dose of a COVID-19 vaccine to be administered to a patient. Credit: Public domain image courtesy of Lisa Ferdinando, U.S. Department of DefenseVaccination against SARS-CoV-2, the virus that causes COVID-19, reduces the risk of serious acute illness in children and adolescents. However, its role in protecting...