ROCHESTER, Minn. — Mayo Clinic researchers, along with colleagues at the University of Iowa, report that a human gut microbe discovered at Mayo Clinic may help treat autoimmune diseases, such as multiple sclerosis. The findings appear in Cell Reports. While probiotics have been used for millennia, there are little data showing how a bacterium can provide...
Author: RMG
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Diabetes drug shows potential as disease-modifying therapy for Parkinson’s disease
A drug commonly used to treat diabetes may have disease-modifying potential to treat Parkinson’s disease, a new UCL-led study suggests, paving the way for further research to define its efficacy and safety. The study, published in The Lancet and funded by The Michael J. Fox Foundation for Parkinson’s Research (MJFF), found that people with Parkinson’s who injected...
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Could probiotics replace antibiotics in wound healing?
The microbiome is known to play a major role in gut health, but what about our skin? Billions of bacteria reside there, and the probiotic types may hold great potential to prevent infections during wound healing. Our skin provides a natural barrier to the environment. This is crucial for our health, as skin protects us...
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The nasal spray that will keep you safe during your holiday flight: Packed full of anti-allergy drugs, it prevents blood clots in the legs during long-haul journeys
Anti-allergy drugs that suppress certain immune cells protect mice against DVT If effective in humans, such drugs could replace treatments that cause bleeding As they are already approved for allergies, they could soon be available for DVT Experts advise people reduce their DVT risk by staying active on flights for now DVT affects around 600,000...
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New botulinum neurotoxin discovered — potential to treat a number of medical conditions
Botulinum toxins are currently used on more than 80 medical conditions including Muscle spasms, Overactive bladder, Chronic migraine, Cervical dystonia, Sweating and Cerebral Palsy (CP). The new toxin, Botulinum neurotoxin type X (BoNT/X), has the potential to open up a new field of toxin therapeutics related to intracellular membrane trafficking and secretion. Since Botulinum neurotoxins...
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Of mice and cheeseburgers: Experimental drug reverses obesity-related liver disease
A drug developed at the University of Rochester Medical Center protected mice from one of the many ills of our cheeseburger and milkshake-laden Western diet—non-alcoholic fatty liver disease. In a study out today in the journal JCI Insights, scientists report that a drug called “URMC-099” reversed liver inflammation, injury and scarring in animals fed a diet high...
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New treatment approved for acute myeloid leukemia
(HealthDay)—The combination chemotherapy drug Vyxeos (daunorubicin and cytarabine) has been approved by the U.S. Food and Drug Administration as the first treatment for certain high-risk types of acute myeloid leukemia (AML). AML is an aggressive blood cancer that forms in the bone marrow. “Vyxeos combines two commonly used chemotherapies into a single formulation that may help...
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FDA approves Mavyret for Hepatitis C
The U.S. Food and Drug Administration today approved Mavyret (glecaprevir and pibrentasvir) to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis, including patients with moderate to severe kidney disease and those who are on dialysis. Mavyret is also approved for adult patients with HCV genotype...
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Common allergy drugs may prevent blood clots
Deep vein thrombosis is a dangerous yet preventable condition. Conventional treatment poses a serious risk of bleeding, but a new study offers hope for a different therapeutic approach and prevention strategy. The Centers for Disease Control and Prevention (CDC) report that up to 900,000 people in the United States live with deep vein thrombosis(DVT) and pulmonary embolism (PE). It is...
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Researchers Have Found a Drug That Can Help Slow the Spread of Multiple Cancers
IN BRIEF Scientists working with Cancer Research UK have discovered that a drug developed to treat organ fibrosis can block an enzyme that assists in the spread of cancer cells. In tests conducted on mice, it was able to reduce the size of tumors by up to 50 percent. SLOWING DOWN CANCER Cancer is one...