by Perelman School of Medicine at the University of Pennsylvania Individuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as shown in the bottom two quadrants, compared to individuals without AD, shown in the top two quadrants. Credit: Penn Medicine A gene encoding a protein linked to tau production—tripartite...
Author: RMG
Pioneering Stem Cell Therapy Offers New Hope for Epilepsy Treatment
This experimental therapy, called NRTX-1001, has the potential to offer drug-resistant temporal lobe epilepsy patients a non-destructive cure for their seizures. The injected cells, derived from human stem cells, are aimed at restoring brain balance and calming seizures. Early results show a more than 90% reduction in seizure frequency in initial patients post-treatment. Key Facts:...
Patients with Breast Cancer Age Faster Than Cancer-Free Women
Published on: July 25, 2023 Alex Biese Receiving a diagnosis of breast cancer and radiation treatment were both associated with increased rates of biological aging among patients who participated in a recent study. Women who have received a diagnosis of and treatment for breast cancer tend to age faster than cancer-free women, according to a...
Scientists Discover RELMalpha Protein Protects Females Against Obesity
By UNIVERSITY OF CALIFORNIA, RIVERSIDE JULY 26, 2023 Scientists have conducted a study using a mouse model to understand sex differences in obesity. They found that female mice, compared to males, are more resistant to obesity and inflammation due to a higher secretion of an immune protein called RELMalpha. The study reveals a crucial ‘RELMalpha–eosinophil–macrophage axis’ in...
Stanford scientists have hatched a new type of drug that can turn a cancer promoter into a cancer killer
Lei Lei Wu News Reporter Stanford scientists have hatched a new type of drug that can turn a cancer promoter into a cancer killer. In a study published in Nature Wednesday, researchers led by Stanford biochemists Nathanael Gray and Jerry Crabtree detailed how they developed a drug that can flip a protein that typically promotes the growth...
Magic mushrooms found to reduce anorexia nervosa psychopathology
by Justin Jackson, Medical Xpress Eating Disorder Psychopathology over time, by Participant. Scores represented are global scores calculated from the Eating Disorder Examination for all participants. Credit: Nature Medicine (2023). DOI: 10.1038/s41591-023-02455-9 Researchers at the University of California at San Diego have studied the effects of magic mushrooms as a therapeutic in treating anorexia nervosa. In their paper,...
Study determines object-related information is distributed across CA1 neurons in the hippocampus
by Ingrid Fadelli, Medical Xpress The y-axis shows how easy it is to predict whether an object is currently present in the environment, based on neural population activity (“decoding accuracy”). If the score is 1, we can always predict whether the object is present or not; if the score is 0.5, our prediction is not...
Joint Effort: CBD Not Just Innocent Bystander in Weed
F. Perry Wilson, MD, MSCE February 13, 2023 Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I’m Dr F. Perry Wilson of the Yale School of Medicine. I visited a legal cannabis dispensary in Massachusetts a few years ago, mostly to see what the hype was about. There I was, knowing basically...
COVID-19 can cause inflammation that results in bone loss, higher fracture risk
by Nadine A Yehya, University of California 3D renderings of L5 lumbar spine segments showing SARS-CoV-2 induced systemic bone loss in both male and female mice. Credit: University of California A UC Davis Health study that looked at acute bone loss in mice who had COVID-19 showed that SARS‐CoV‐2 infection can cause significant changes in...
Got high blood pressure? Why doing the plank or ‘wall-sits’ might be better than going for a swim
By KATE PICKLES HEALTH EDITOR FOR THE DAILY MAIL UPDATED: 05:44 EDT, 26 July 2023 A brisk walk, cycle or swim is often the doctors’ orders when it comes to high blood pressure. But now scientists suggest doing the ‘plank’ or ‘wall-sits’ are better exercises for helping to control hypertension. A review of clinical data found that...