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Tiny, ultra-flexible neural probes without cranial surgery open up new potentials for in vivo brain research
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Tiny, ultra-flexible neural probes without cranial surgery open up new potentials for in vivo brain research

by Justin Jackson, Medical Xpress Micro-endovascular (MEV) probe selectively implanted into a curved branch for neural recording across the blood vessel wall. The MEV probe (yellow), which is designed to curve into branched (vs. straight) blood vessels, is selectively injected into the branched vessel by saline flow through the microcatheter (cyan) in which it was...

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Oral Tau Inhibitor Continues to Show Promise in Alzheimer’s

Megan Brooks July 21, 2023 Treatment with an experimental oral tau aggregation inhibitor, hydromethylthionine mesylate (HMTM), led to a statistically significant reduction in an established biomarker of neurodegeneration in Alzheimer’s disease (AD) in the LUCIDITY phase 3 trial. Blood concentrations of neurofilament light chain (NfL) showed a 93% reduction in change over 12 months in participants receiving...

Bacteria-hunting viruses help diagnose and treat UTIs
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Bacteria-hunting viruses help diagnose and treat UTIs

By Michael Irving July 23, 2023 Bacteriophages seen under the microscope Matthew Dunne / ScopeM / ETH Zurich Viruses may get a bad rap, but some of them can be helpful to fight off bacterial infections. Scientists at ETH Zurich have demonstrated a new way to use them to diagnose which bacteria is causing a...

Grow-your-own stem cells may repair Parkinson’s damage
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Grow-your-own stem cells may repair Parkinson’s damage

By Bronwyn Thompson July 24, 2023 Parkinson’s disease patients may one day use their own cells to regrow neurons Depositphotos A new stem cell therapy for Parkinson’s disease is one step closer to human trials after scientists were able to successfully rebuild neural damage in an animal model. Researchers from Scripps Research and Cardiff University...

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‘Strikingly Positive’ Effect of Novel MS Agent

Nancy A. Melville June 09, 2023 UPDATED June 12, 2023 // Editor’s note: This story has been updated with additional comments from Dr Ahmed Obeidat from the Medical College of Wisconsin. Frexalimab, a novel, second-generation anti-CD40L antibody, shows “strikingly positive” effects in the treatment of relapsing multiple sclerosis (MS), significantly reducing disease activity. “We should be very excited about these results,...

Spiral brain-computer interface slips into ear canal with no loss of hearing
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Spiral brain-computer interface slips into ear canal with no loss of hearing

by Bob Yirka, Medical Xpress Design of in-ear bioelectronics. a Schematic diagram of in-ear EEG recording by SpiralE. b Pictures of SpiralE conformally adapting to the inner wall of the ear canal. Upper-right inset is a photograph captured by a medical endoscope. Lower-right inset shows the irregular three-dimensional structure of SpiralE after removal form ear....

Study shows how the brain coordinates neuronal processing and communication during sleep
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Study shows how the brain coordinates neuronal processing and communication during sleep

by Ingrid Fadelli, Medical Xpress The recorded signal reveals when neurons fire. Credit: Christian Burkert / Volkswagen-Stiftung / Universität Bonn. Past neuroscience studies have shown that while humans are sleeping, the brain remains highly active, consolidating memories and removing toxins accumulated during waking hours. While memory consolidation during sleep is a widely documented phenomenon, the...

Enhanced light sensitivity may contribute to Alzheimer’s ‘sundowning,’ disease progression
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Enhanced light sensitivity may contribute to Alzheimer’s ‘sundowning,’ disease progression

UNIVERSITY OF VIRGINIA HEALTH SYSTEM IMAGE: HEATHER FERRIS, MD, PHD, OF THE UNIVERSITY OF VIRGINIA SCHOOL OF MEDICINE’S DIVISION OF ENDOCRINOLOGY AND METABOLISM, FOUND THAT ENHANCED LIGHT SENSITIVITY MAY PLAY A KEY ROLE IN ALZHEIMER’S DISEASE. CREDIT: UVA HEALTH New Alzheimer’s research from UVA Health suggests that enhanced light sensitivity may contribute to “sundowning” – the worsening...

Constipation linked to 73% higher risk of cognitive decline
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Constipation linked to 73% higher risk of cognitive decline

New research links constipation with a higher risk of cognitive decline. Image credit: tifonimages/Getty Images. In a series of new studies, researchers investigated the link between constipation and cognitive decline. They found that one bowel movement every 3 days or less frequently is linked to higher levels of cognitive decline alongside certain changes in the...