New research has shown evidence that anti-epileptic drugs (AEDs) reduce bone density in children and therefore lead to an increase in the number of fractures if used for more than a year. The study by the Murdoch Children’s Research Institute (MCRI), in conjunction with the Royal Melbourne Hospital (RMH), has prompted experts to highlight the...
Category: <span>Diagnostic</span>
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First seeds of kidney cancer sown in adolescence
Insights from this study present an opportunity to develop approaches for early detection and early intervention in kidney cancer The earliest critical genetic changes that can lead to kidney cancer have been mapped by scientists. The first key genetic change occurs in childhood or adolescence, and the resulting cells follow a consistent path to progress...
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Weight loss is an important predictor of cancer
Unintended weight loss is the second highest risk factor for some forms of cancer, concludes the first robust research analysis to examine the association. A team led by the Universities of Oxford and Exeter conducted the first systematic review and meta-analysis to examine all available evidence on the association between weight loss and cancer in primary care. Their...
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The absence of a single mitochondrial protein causes severe inflammation
A study performed at IRB Barcelona supports the notion that mitochondrial defects underlie a set of diseases of unknown origin that involve chronic muscle inflammation IMAGE: MITOCHONDRIAL DNA STRESS (IN RED) TRIGGERS THE INFLAMMATORY RESPONSE IN MOUSE MUSCLE CELLS DEVOID OF OPA1 (NUCLEI IN GREEN). CREDIT: AIDA RODRÍGUEZ, IRB BARCELONA The link between mitochondria and inflammation...
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Large-scale study links PCOS to mental health disorders
Women with polycystic ovary syndrome (PCOS), the most common hormone condition among young women, are prone to mental health disorders, and their children face an increased risk of developing attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. PCOS...
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There’s a better way to screen for cervical cancer
A new study in the Journal of the National Cancer Institute, published by Oxford University Press, indicates that high-quality cervical cancer screening can be done effectively using a completely automated approach. The researchers involved in the study indicate that automated technology could increase cervical screening coverage in underserved regions. Cervical cancer is caused by persistent infection...
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Severity of menopause symptoms could help predict heart disease
New study evaluates the effect of menopause and depression on vascular function THE NORTH AMERICAN MENOPAUSE SOCIETY (NAMS) CLEVELAND, Ohio (April 11, 2018)–Heart disease remains the leading cause of death in women. A study of 138 menopausal women examined the association of mood, symptoms, and quality of life measures with the key markers of vascular...
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Blood test may predict future risk of cardiovascular events
Study of 27,000 women finds that branched-chain amino acid levels in the bloodstream are as predictive of heart disease as LDL cholesterol, other risk factors BRIGHAM AND WOMEN’S HOSPITAL Despite heart disease and type 2 diabetes being among the leading causes of death in the U.S., the mechanisms leading to and linking these two diseases...
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Study confirms link between traumatic brain injury and dementia
One of the largest studies of its kind, 2.8 million people, finds that TBIs’ number and severity heighten risk. UNIVERSITY OF WASHINGTON HEALTH SCIENCES/UW MEDICINE The risk of dementia, including Alzheimer’s, was significantly higher in people who had experienced a traumatic brain injury (TBI) than with people who had no history of TBI, according to...
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Researchers identify peptide produced during cartilage deterioration as a potential source of osteoarthritis pain
Credit: Rush University Medical Center Osteoarthritis is one of the most common causes of chronic pain in the world. More than 30 million people in the United States alone suffer from osteoarthritis, or OA, which can affect any moveable joint of the body, including the knees, hips and hands. OA normally manifests itself as a...