(HealthDay)—For older adults, dipeptidyl peptidase 4 inhibitors (DPP-4Is) are not associated with increased risk of acute pancreatitis, according to a study published online April 4 in Diabetes Care. Jin-Liern Hong, Ph.D., from the University of North Carolina at Chapel Hill, and colleagues examined the risks of acute pancreatitis among U.S. Medicare beneficiaries, aged 66+ years, initiating DDP-4Is versus...
Category: <span>Diagnostic</span>
Vitamin D blood test may one day speed bipolar diagnosis in kids
Finding a reliable blood marker could offer help to doctors and parents, study suggests COLUMBUS, Ohio – A blood test may have the potential to speed accurate diagnosis – and proper treatment – of bipolar disorder in children, new research suggests. Researchers at The Ohio State University found that children with bipolar disorder had higher...
Allina study shows patients with very small breast tumors may forgo lymph node biopsies
Study examined the outcomes of 294 patients, found only 1.5 percent had positive lymph nodes How to treat patients who have microinvasive breast cancer – tumors that are 1 mm or less in size (the thickness of a dime) — is somewhat controversial. Can these tiny tumors affect the lymph nodes and spread cancer to...
New ‘Pan-Cancer’ analysis reveals the common roots of different cancers
In the largest study of its kind, cancer researchers analyzed and classified over 10,000 tumors from 33 cancer types to trace connections between different cancers. Typically cancers are classified by where they originate in the body–think breast cancer, stomach cancer, and so on. But a collaboration called the Pan-Cancer Initiative, launched in 2012 at a...
The relevance of GABA for diabetes is highlighted in two new studies
Dynamic interactions between the nervous system, hormones, and the immune system are normally on-going but in diabetes, the balance is disturbed. The two studies published in EBioMedicine by an international research team from Uppsala University highlight the importance of the neurotransmitter beta-aminobutyric acid (GABA) in both Type 1 and Type 2 diabetes. GABA is synthesized by an...
Researchers identify risk genes for amyotrophic lateral sclerosis
The largest analysis to date of genetic data in amyotrophic lateral sclerosis (ALS) – the muscle-crippling neurodegenerative disease that afflicted the late astrophysicist Stephen Hawking and cut short the career of iconic Yankee baseball slugger Lou Gehrig – has identified two previously unrecognized genetic risks that are significantly associated with the disease. In the...
New blood test useful to detect people at risk of developing Alzheimer’s disease
Heidelberg, 6 April 2018 – There is, as yet, no cure for Alzheimer’s disease. It is often argued that progress in drug research has been hampered by the fact that the disease can only be diagnosed when it is too late for an effective intervention. Alzheimer’s disease is thought to begin long before patients show...
New blood test found to predict onset of TB up to two years in advance
April 6, 2018 — A new blood test has been found to more accurately predict the development of tuberculosis up to two years before its onset in people living with someone with active TB, according to research published online in the American Journal of Respiratory and Critical Care Medicine, an American Thoracic Society journal. IMAGE: TB blood...
Vitamin D blood test may one day speed bipolar diagnosis in kids
Finding a reliable blood marker could offer help to doctors and parents, study suggests COLUMBUS, Ohio – A blood test may have the potential to speed accurate diagnosis – and proper treatment – of bipolar disorder in children, new research suggests. Researchers at The Ohio State University found that children with bipolar disorder had higher...
Risk of type 1 diabetes climbs when one population of T cells falls
BOSTON – (April 5, 2018) – In autoimmune diseases such as type 1 diabetes, some of the immune system’s T cells mistakenly attack the body’s own cells, while protective T regulatory cells try to defend against that attack. Scientists at Joslin Diabetes Center have shown in a mouse model of type 1 diabetes that animals...