A team of scientists led by Professor Lim Chwee Teck, Principal Investigator at the Mechanobiology Institute, Singapore (MBI) and the Department of Biomedical Engineering at the National University of Singapore (NUS) and NUS Ph.D. graduate Dr. Khoo Bee Luan, has developed a novel and robust cancer cell-based assay that could help clinicians to diagnose cancer,...
Category: <span>Diagnostic</span>
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New needle device to revolutionize biopsies and reduce scarring
With at least two in three Australians diagnosed with skin cancer before the age of 70, monitoring moles and skin is vital in detecting skin cancer early for a generation of people who spent much of their upbringing in the sun (often with little to no protection). To meet the massive unmet need in this...
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Student Engineers Create Foot Inspection Device for People with Diabetic Neuropathy – diagnostic
People suffering from diabetic neuropathy often can’t feel the soles of their feet. They can also develop dangerous wounds on those soles that may not be detected early enough, sometimes leading to infections, debridements, and amputations. There aren’t a lot of cheap options for keeping an eye on the bottoms of the feet. Mirrors are...
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How much will this hurt? Brain waves may hold the answer
We all feel pain, but our experiences are not equal. A new study demonstrates that by measuring brain activity, we might be able to predict who will be more sensitive to pain. Brain waves may help doctors to understand who is more susceptible to pain. Pain is a strange phenomenon. How painful a particular injury...
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Early age-related macular degeneration linked to high HDL
(HealthDay)—There is a higher risk for early age-related macular degeneration (AMD) in individuals with high plasma high-density lipoprotein cholesterol levels, according to a study published online March 29 in JAMA Ophthalmology. Valentine Saunier, M.D., from the Université de Bordeaux in France, and colleagues describe the incidence and associated risk factors of AMD among 659 residents of...
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Aggressive Meningioma Linked to Transcription Factor Activity
NEW YORK (GenomeWeb) – A new integrated ‘omics analysis suggests that the transcription factor FOXM1 can act as a meningioma driver, prompting proliferation, progression, and relatively poor outcomes in individuals with the disease, a primary central nervous system tumor that forms in meninges tissue surrounding the brain and spinal cord. As they reported online today in Cell Reports,...
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Researchers describe the dynamics of P. falciparum infections in adults without fever
Health care workers visit households in Southern Mozambique to identify men infected with the malaria parasite but presenting no symptoms. Credit: Beatriz Galatas Asymptomatic malaria occurs when parasites are present in an individual’s blood, but do not cause fever or other symptoms. These “afebrile” infections can be detected either by classical diagnostic tests (if there...
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Non-invasive test can detect Urothelial cancer
(HealthDay)—UroSEEK, which uses DNA recovered from cells shed into urine, can detect urothelial cancer, according to a study published online March 20 in eLife. Simeon U. Springer, from the Ludwig Center for Cancer Genetics and Therapeutics in Baltimore, and colleagues developed a test to detect urothelial neoplasms that incorporates massive parallel sequencing assays for mutations in...
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Accurately diagnosing genetic disease prevents cancer, saves lives
A single, upfront genomic test is more effective for detecting Lynch syndrome in colorectal cancer (CRC) patients than the traditional multiple, sequential testing approach, according to new clinical data reported by The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) Researchers say...
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NUS scientists develop novel chip for fast and accurate disease detection at low cost
A novel invention by a team of researchers from the National University of Singapore (NUS) holds promise for a faster and cheaper way to diagnose diseases with high accuracy. Professor Zhang Yong from the Department of Biomedical Engineering at the NUS Faculty of Engineering and his team have developed a tiny microfluidic chip that could...