Lou Schuler Clinicians are well aware of the benefits of physical activity — and the consequences of inactivity. Managing the diseases associated with inactivity — heart disease, type 2 diabetes, hypertension — falls to physicians. So one might assume they routinely prescribe exercise to their patients, just as they would statins, insulin, or beta-blockers. But...
Category: <span>Editorial</span>
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Bad Blood: Could Brain Bleeds Be Contagious?
F. Perry Wilson, MD, MSCEDISCLOSURES Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I’m Dr F. Perry Wilson of the Yale School of Medicine. How do you tell if a condition is caused by an infection? It seems like an obvious question, right? In the post–van Leeuwenhoek era we...
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Long-Term Results Show Major Advance in Endometrial Cancer
Maurie Markman, MDDISCL OSURES October 04, 2023 I’m Dr Maurie Markman from City of Hope, and I would like to discuss a fascinating, long-term, follow-up study of a trial that was completed many years ago but addresses a very important, clinically related matter. The trial I am referring to, published in the Journal of Clinical Oncology, is...
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Fatty Liver: A Primary Care Approach
Neil Skolnik, MD I’m Dr Neil Skolnik. Today, we are going to talk about two guidelines: the American Association for the Study of Liver Diseases (AASLD) clinical assessment and management of nonalcoholic fatty liver disease (NAFLD) and the American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver...
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Another Study Ties Statins to T2D: Should Practice Change?
Marilynn Larkin October 30, 2023 Studies have shown links between statin use and type 2 diabetes (T2D) for more than a decade. A US Food and Drug Administration label change for the drugs warned in 2012 about reports of increased risks of high blood glucose and glycosylated hemoglobin (A1c) levels. However, in the same warning, the FDA...
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Inappropriate Cardiac Imaging Triggers Too Many Alarms
Ann Thomas, MD, MPH October 26, 2023 A dizzying array of cardiac imaging tools allows clinicians to visualize the structure and function of the heart better than ever before, making it difficult to keep up with appropriate indications for their use. And it has become common for patients to present to clinic worried about alarms triggered by...
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This Drug Works, but Wait Till You Hear What’s in It
F. Perry Wilson, MD, MSCEDISCLOSURES October 24, 2023 Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I’m Dr F. Perry Wilson of the Yale School of Medicine. As some of you may know, I do a fair amount of clinical research developing and evaluating artificial intelligence (AI) models, particularly machine learning...
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GLP-1 Agonists and Suicide Risk: What Action Should Be Taken?
Boris Hansel, MD, PhD A statement from the European Medicines Agency (EMA) about semaglutide and, more generally, glucagon-like peptide 1 (GLP-1) agonists recently caused a stir. Could these medicines lead to patients taking their own lives? Medical Authorities AlertThe EMA published a press release in early July 2023 to announce that a review is underway...
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AI in Medicine Has a Major Cassandra Problem
F. Perry Wilson, MD, MSCEDISCLOSURES October 17, 2023 Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I’m Dr F. Perry Wilson of the Yale School of Medicine. Today I’m going to talk to you about a study at the cutting edge of modern medicine, one that uses an artificial intelligence model...
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Multivitamins and Dementia: Untangling the COSMOS Study Web
Christopher Labos, MD CM, MSc I have written before about the COSMOS study and its finding that multivitamins (and chocolate) did not improve brain or cardiovascular health. So I was surprised to read that a “new” study found that vitamins can forestall dementia and age-related cognitive decline. Upon closer look, the new data are neither...