by University of Southern California The free high-resolution photo of writing, hand, number, line, measure, weight, fitness, measurement, close up, font, handwriting, organ, calligraphy, scales, shape, loss, emotion, pound, measuring, weight scale, weight loss, overweight. Credit: Pxhere With advances in analyzing human DNA, some well-studied populations have benefited from insights about how their health is affected...
Danielle Ternes/BioPharma Dive AUTHOR Ned Pagliarulo@NedPagliarulo PUBLISHED Feb. 12, 2021 The toxic globules of sugar and fat slowly pile up in the body’s cells, accumulating in blood vessels and in major organs like the kidney and heart. Typically, special-purpose proteins within the cell would tear apart and break down the toxins. But for people with...
by Rensselaer Polytechnic Institute A compound found in green tea stabilizes an anti-cancer protein known as the “guardian of the genome.” Credit: Rensselaer Polytechnic Institute An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the “guardian of the genome” for its ability to repair DNA damage or destroy...
IOS PRESS IMAGE: TIMELINE OF SOME OF THE KEY EVENTS ESTABLISHING ANTICIPATION AS A GENUINE BIOLOGICAL PHENOMENON AND SOMATIC EXPANSION AS CONTRIBUTING TOWARD HUNTINGTON’S DISEASE PATHOLOGY. CREDIT: : DARREN G. MONCKTON IN “THE CONTRIBUTION OF SOMATIC EXPANSION OF THE CAG REPEAT TO SYMPTOMATIC DEVELOPMENT IN HUNTINGTON’S DISEASE: A HISTORICAL PERSPECTIVE, ” JOURNAL OF HUNTINGTON’S DISEASE...
by Delthia Ricks , Medical Xpress Credit: CC0 Public Domain If an opinion poll were taken for the most popular component of mammalian cells, the result probably would be a 50-50 split: Half of respondents would likely vote hands down for the nucleus and the other half for the mitochondria—a decision that in no way...
UNIVERSITY OF CALIFORNIA – SAN FRANCISCO For all their importance as a breakthrough treatment, the cancer immunotherapies known as checkpoint inhibitors still only benefit a small minority of patients, perhaps 15 percent across different types of cancer. Moreover, doctors cannot accurately predict which of their patients will respond. A new study finds that inherited genetic...
by Arizona State University Tian’s research reveals a novel winner-takes-all resource competition between synthetic gene circuits within one host cell. Credit: Xiaojun Tian/ASU. A new process for inserting synthetic gene circuits into host cells, developed by a team of bioengineers at Arizona State University, has broad implications for improving the effectiveness of a range of disease therapies. Synthetic...
by Calley Jones, Broad Institute of MIT and Harvard Credit: CC0 Public Domain A new method for studying gene function shows how high blood sugar and bone density are connected in diabetes patients. Scientists have discovered thousands of genetic variants—tiny changes in the genetic code—that are linked to increased risk of various diseases. Learning what these variants...
by National University of Ireland, Galway Credit: CC0 Public Domain Researchers at NUI Galway have identified genomic signatures in women developing the most common type of breast cancer that can be associated with long-term survival. The NUI Galway team analyzed the genomes of breast cancer patients to look for associations with survival rates using advanced statistical techniques....
by Michael Haederle, University of New Mexico Health Sciences Center Credit: Pixabay/CC0 Public Domain Tuberous sclerosis complex (TSC) afflicts as many as two million people around the world, affecting multiple organs, including lungs, brain, skin and kidneys. In about 80 percent of cases, it causes cysts and benign tumors to form in the kidney, eventually...
