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Spontaneous cell fusions amplify genetic diversity within tumors
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Spontaneous cell fusions amplify genetic diversity within tumors

by  H. Lee Moffitt Cancer Center & Research Institute Credit: CC0 Public Domain Evolution within groups of tumor cells follows the principles of natural selection, as evolution in pathogenic microbes. That is, the diversity of cellular characteristics within a group leads to differences in the ability of cells to survive and divide, which leads to selection for cells...

Fascinating new videos capture human RNA like it’s ‘never been seen in nature’
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Fascinating new videos capture human RNA like it’s ‘never been seen in nature’

by Chris Melore EVANSTON, Ill. — The human body has trillions of cells. Each one contains the building blocks of life and now, for the first time, a study has discovered how some of those building blocks operate. Researchers from Northwestern University say they’ve created the first-ever, data-driven videos which reveal how RNA molecules twist and fold to...

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Gene-cutting system may play second role as a genetic dimmer switch

Reviewed by Emily Henderson, B.Sc. Jan 19 2021 In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting system CRISPR-Cas9 — as a genetic dimmer switch for CRISPR-Cas9 genes. Its role of dialing down or dimming CRISPR-Cas9 activity may help...

Blood type co-determines composition of the gut microbiome
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Blood type co-determines composition of the gut microbiome

by  Kiel University High-throughput sequencing can be used to obtain the genetic information of a living organism within a few hours. Credit: SoulPicture|Kiel, IKMB Uni Kiel For several years, scientists worldwide have been investigating the extent to which microorganisms living in and on the human body influence central life processes and thus health and disease. Today...

Coenzyme Q10 could treat mitochondrial diseases, colon cancer, thyroid carcinoma and Crohn’s disease
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Coenzyme Q10 could treat mitochondrial diseases, colon cancer, thyroid carcinoma and Crohn’s disease

by  University of Granada Graphic overview of the research. Credit: University of Granada Coenzyme Q10 (CoQ10) is a molecule essential for life that is synthesized in the cells of our organs and tissues, but is also acquired through diet Scientists from the University of Granada demonstrate for the first time that a CoQ10 supplement is capable of modulating hydrogen...

Genetic factors involved in shaping composition of human gut microbiome, international research team finds
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Genetic factors involved in shaping composition of human gut microbiome, international research team finds

by  University of Bristol Credit: Unsplash/CC0 Public Domain Human genes have an impact on shaping our gut ecosystem according to new evidence from the international MIBioGen consortium study involving more than 18,000 people. The findings, led by the University Medical Center Groningen, Netherlands and involving researchers at the University of Bristol, are published in Nature Genetics. The last decade...

Tiny molecules with a big impact
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Tiny molecules with a big impact

by BIH at Charité  Influence of genetic variants on metabolite concentration: the higher the line, the greater the statistical probability that the genetic variants actually have an influence. Colors indicate the biochemical classes of the molecules. Credit: BIH/Maik Pietzner The human organism requires a variety of small molecules, such as sugars or fats, in order...

Inferring human genomes at a fraction of the cost promises to boost biomedical research
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Inferring human genomes at a fraction of the cost promises to boost biomedical research

by  Swiss Institute of Bioinformatics From left to right: Robin Hofmeister, Diogo Ribeiro, Simone Rubinacci and Olivier Delaneau Credit: Delaneau Group Thousands of genetic markers have already been robustly associated with complex human traits, such as Alzheimer’s disease, cancer, obesity, or height. To discover these associations, researchers need to compare the genomes of many individuals at millions of...

Precision health in the palm of your hand
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Precision health in the palm of your hand

by Steve Crang,  University of Michigan Precision health is an approach to wellness that takes into account variability in genes, environment, and lifestyle for each person. And thanks to advancements in technology, it’s here today. Credit: University of Michigan Precision health is an approach to wellness that takes into account variability in genes, environment, and lifestyle...

Genetics reveals the link between blood insulin and gender: one size doesn’t fit all
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Genetics reveals the link between blood insulin and gender: one size doesn’t fit all

by Natasha Meredith,  University of Surrey Credit: University of Surrey The diverse impact of the genetic makeup in men and women on levels of fasting blood insulin has been identified for the first time in the largest international study of its kind. Publishing their findings in the journal Nature Communications, researchers from the University of Surrey, VIB-KU Leuven, University...