UNIVERSITY OF CALIFORNIA – LOS ANGELES HEALTH SCIENCES IMAGE: EVIE JUNIOR CREDIT: UCLA BROAD STEM CELL RESEARCH CENTER For Evie Junior, living with sickle cell disease has been like running a marathon. “But it’s a marathon where as you keep going, the trail gets rockier and then you lose your shoes,” the 27-year-old said. “It gets harder...
by Estonian Research Council Triin Laisk, a Senior Research Fellow at the Estonian Genome Center. Credit: Reedik Mägi Researchers at the Estonian Genome Center at the University of Tartu have described hitherto undiscovered associations between miscarriage and maternal genes. They have published their findings in Nature Communications. Miscarriage is the most common complication of pregnancy, affecting...
Reviewed by Emily Henderson, B.Sc.Nov 25 2020 Ataxia is a minority disease with genetic origins, known for its neuromuscular alterations due to the selective loss of neurons in the cerebellum, the organ of our nervous systems which controls movement and balance. UB researchers have identified new functions in the ataxin 3 gene (ATXN3) -which causes Machado-Joseph disease, the...
UNIVERSITY OF MAINE A gene known for helping facilitate communication between neurons in the nervous system has been discovered to be connected with Alzheimer’s dementia and cognitive decline, according to a national research team led by The Jackson Laboratory and University of Maine. Catherine Kaczorowski, associate professor and Evnin family chair in Alzheimer’s research at The Jackson Laboratory (JAX),...
by Molly Chiu, Baylor College of Medicine Researchers identified the BICRA gene’s involvement in neural development. Physicians and scientists are constantly on the lookout for new disease genes that can help them understand why patients have undiagnosed medical problems. Often the first clues come from genetic testing that reveals a change or mutation in a gene...
by Trinity College Dublin A fluorescent microscope image with mitochondria highlighted in gold. This healthy cell shows a highly elaborate and well-connected network of mitochondria. Credit: Professor Jane Farrar and Dr Daniel Maloney, Trinity College Dublin Scientists from Trinity College Dublin have developed a new gene therapy approach that offers promise for one day treating an...
by Doug Dollemore, University of Utah Health Sciences Credit: Unsplash/CC0 Public Domain Every 11 minutes, an American dies by suicide. That’s 132 people a day or more than 48,000 annually. For those left behind, the haunting question is why. One emerging factor is family history. Perhaps the most famous example is Ernest Hemingway’s family. In addition to...
Technology Org Science and technology news Posted Today In a new study published in the journal JAMA Psychiatry, researchers at Karolinska Institutet have studied CYP2C19 and CYP2D6 genes impact on treatment with antidepressants and antipsychotic drugs. The study shows that control of the patient’s genotype can be used to individualize the drug treatment and lead to...
by Tel Aviv University Cancer cell during cell division. Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer. The researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic...
UNIVERSITY OF VIRGINIA HEALTH SYSTEM IMAGE: UVA’S SANCHITA BHATNAGAR, PHD, FOUND THAT THE BREAST CANCER ONCOGENE TRIM37 NOT ONLY CAUSES TRIPLE NEGATIVE BREAST CANCER TO SPREAD BUT ALSO MAKES IT RESISTANT TO CHEMOTHERAPY. University of Virginia Cancer Center researchers have identified a gene responsible for the spread of triple-negative breast cancer to other parts of the body...
