by Centenary Institute Centenary Institute researchers have discovered that genetic testing can identify “concealed cardiomyopathies” in nearly a quarter of sudden cardiac arrest (SCA) survivors who seem to have a normal heart. The findings will mean improved diagnosis rates and personalized care for SCA survivors as well as guide the screening of family members who may have the...
by University of Queensland A gene that helps to control inflammation increases the risk of obesity and could be turned off in mice to stop weight gain, a study from The University of Queensland has found. UQ Institute for Molecular Bioscience researcher Dr. Denuja Karunakaran said she was determined to unravel the links between inflammation and...
UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES Over the past decade, scientists have identified hundreds of different genetic variants that increase a person’s risk of developing obesity. But a lot of work remains to understand how these variants translate into obesity. Now scientists at the University of Copenhagen have identified populations of...
Understanding of fibromuscular dysplasia (FMD), a rare blood vessel disease, is making the jump from the laboratory to the clinic with new findings of a genetic variant. Researchers found the mutation in a gene that is associated with classical Ehlers-Danlos Syndrome as well, in multifocal FMD. That means it could help clinicians understand whether a person...
by Children’s Hospital of Philadelphia Researchers from Children’s Hospital of Philadelphia (CHOP) have shown there may be key genetic differences in the causes of attention-deficit hyperactivity disorder (ADHD) between African Americans and people of European ancestry, which may play an important part in how patients of different ethnic backgrounds respond to treatments for this condition. The findings...
MEDICAL UNIVERSITY OF SOUTH CAROLINA IMAGE: PERSONALIZED ALCOHOL TREATMENT Considering a patient’s genetics could inform clinicians which medications would be most effective in controlling cravings and treating alcohol use disorder. Twenty million Americans currently struggle with an alcohol use disorder. Of those who seek treatment, only 20% receive medications, either alone or in addition to...
UNIVERSITY OF EASTERN FINLAND A new study conducted by researchers at the University of Eastern Finland found that the PLCG2-P522R genetic variant, which protects against Alzheimer’s disease, enhances several key functions of immune cells. The results obtained in the study highlight the importance of immune cells as a target of future development of new therapies for Alzheimer’s...
by Bob Yirka , Medical Xpress Credit: Pixabay/CC0 Public Domain A team of researchers from Italy, the U.K. and the U.S. has isolated a number of immune cell-related genetic variants that may impact autoimmune conditions. In their paper published in the journal Nature Genetics, the group describes the host of tools and techniques they used to...
Mouse studies show gene therapy can cause big drop in latent infections. It takes a persistent scientist to stop a persistent virus. A decade ago, Fred Hutchinson Cancer Research Center virologist Dr. Keith Jerome began exploring the idea that lifelong infections with herpes viruses might be cured by using the DNA-cutting tools of gene therapy. Initial research...
SCRIPPS RESEARCH INSTITUTE IMAGE: CLAUDIO JOAZEIRO, PHD, IS A PROFESSOR IN THE SCRIPPS RESEARCH DEPARTMENT OF MOLECULAR MEDICINE JUPITER, FL — Failures in a quality control system that protects protein-building fidelity in cells can lead to motor neuron degeneration and related diseases, according to a new study from an international team co-directed by Scripps Research...
