B: UNIVERSITY OF BRISTOL A new study led by the University of Bristol has shown a common eye condition, glaucoma, could be successfully treated with a single injection using gene therapy, which would improve treatment options, effectiveness and quality of life for many patients. Glaucoma affects over 64 million people worldwide and is a leading...
by University of Cambridge Researchers trying to turn off a gene that allows cancers to spread have made a surprising U-turn. By making the gene overactive and functional in the hearts of mice, they have triggered heart cell regeneration. Since adult hearts cannot usually repair themselves once damaged, harnessing the power of this gene represents...
CLEMSON UNIVERSITY CLEMSON, South Carolina — Scientists believe about 25 percent of the differences in human life span is determined by genetics — with the rest determined by environmental and lifestyle factors. But they don’t yet know all the genes that contribute to a long life. A study published March 5, 2020, in PLOS Biology...
Reviewed by James Ives, M.Psych. (Editor)Apr 10 2020 A new Finnish study demonstrated the benefits of large-scale genomic information in estimating the risk of onset for cardiac diseases, diabetes and common cancers. The findings, based on the FinnGen research dataset encompassing more than 135,000 Finns, show that new tools based on genomic data are helpful...
by Greta Friar, Whitehead Institute for Biomedical Research Multiple sclerosis (MS) is a debilitating disease in which the body’s own immune system attacks itself and can, over time, permanently destroy the protective sheaths, or myelin, around nerve fibers in the brain. Myelin insulates nerve cells and facilitates the transmission of messages along them. When the...
Researchers at CHOP and University of Pennsylvania developed an online tool to refine results from RNA sequencing obtained from clinically accessible tissues CHILDREN’S HOSPITAL OF PHILADELPHIA Philadelphia, March 31, 2020 – DNA sequencing is becoming a more commonplace method for detecting diseases and improving precision medicine. Because DNA sequencing does not detect all possible disease-causing...
VIB (THE FLANDERS INSTITUTE FOR BIOTECHNOLOGY) Screening DNA of Parkinson’s patients in the Christine Van Broeckhoven laboratory (VIB-UAntwerpen Center for Molecular Neurology) identified a new risk gene for Parkinson’s disease. Mutations in ATP10B resulted in loss of ATP10B protein. The function of the ATP10B gene was revealed by the Peter Vangheluwe lab (KU Leuven, Laboratory...
by University of British Columbia Researchers from the University of British Columbia (UBC) and the Central South University (CSU) in China have for the first time identified a gene that increases the risk of Alzheimer’s disease. In the study, published recently in the journal JCI Insight, the researchers found two mutations in the gene endothelin-converting...
New insight on DNA repair in yeast adds to our understanding of why DNA repair processes fail to function properly in disease ELIFE Scientists have revealed an important mechanism in the repair of DNA double-strand breaks, according to new research published today in eLife. The discovery will help our understanding of why DNA repair processes...
VANDERBILT UNIVERSITY MEDICAL CENTER Vanderbilt researchers have identified haplotypes, ancestral fragments of DNA, that are associated with hereditary prostate cancer (HPC) in a first-of-its-kind genomic study made possible by the study of prostate cancer patients with family histories of the disease. The researchers analyzed the Nashville Familial Prostate Cancer Study (NFPCS), in an investigation comparing...
