MAY 31, 2024 by The Mount Sinai Hospital Schematic showing the structures of U4 and U6 RNAs, and the interactions between them. Mutations in the highlighted regions of U4 cause a neurodevelopmental disorder that affects tens of thousands. Credit: Lab of Ernest Turro, Ph.D., at Icahn Mount Sinai. Researchers at the Icahn School of Medicine...
Category: <span>Genetics</span>
LJI scientists develop new method to match genes to their molecular ‘switches
New research may help scientists hunt down solid tumors and better diagnose disease Peer-Reviewed PublicationLA JOLLA INSTITUTE FOR IMMUNOLOGY THE NEW RESEARCH WAS LED BY LJI PROFESSOR ANJANA RAO, PH.D., (LEFT) AND LJI ASSOCIATE PROFESSOR FERHAT AY, PH.D. LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) have developed a new computational method for...
Genetic Cause of Rare Neurological Disease Found After 25-Year Search
HEALTH 15 May 2024ByDAVID NIELD Brain tissue scan, with the bright red ring showing a protein clump that only shows up in patients with SCA4. (Mandi Gandelman) You might not have heard of spinocerebellar ataxia type 4 (SCA4), as it’s an incredibly rare condition – but after a quarter of a century of looking, the...
Gene editing breakthrough could soon cure herpes for good
(© DOC RABE Media – stock.adobe.com)HEALTH & MEDICAL NEWS by Chris Melore MAY 14, 2024 SEATTLE — A revolutionary new treatment may forever get rid of the painful and embarrassing blisters that come from a herpes flare-up. The herpes viruses that cause either cold sores around the mouth or blisters near the genitals stick around...
Researchers discover new pathway to cancer cell death from chemotherapy
MAY 16, 2024 by Netherlands Cancer Institute Organoid of a patient with colon cancer, treated (right) and not treated with the chemotherapy etoposide. The treatment causes DNA damage and a reduction in protein synthesis. This triggers a stress signal that causes the cells to die. Orange: marker for DNA damage. Green: marker for protein synthesis....
Important Gene in the Fight Against Prostate Cancer Identified
Men with mutations in a particular gene are at greater risk of developing metastases after prostate cancer.News Published: May 17, 2024 | Original story from Aarhus University Credit: iStock. Finding out that cancer has spread is always unwelcome news. A study from Aarhus University has identified a gene that determines whether patients with prostate cancer...
New mechanisms underlying tumor variety in brain cancers discovered
MAY 20, 2024 by Melissa Rohman, Northwestern University High-grade meningiomas are distinguished by regionally distinct intratumor immune infiltration, MAPK signaling, PI3K-AKT signaling, and cell proliferation. Credit: Amy B. Heimberger, MD, Ph.D. Investigators have discovered new mechanisms underlying the diversity of characteristics within a single tumor, as well as treatment resistance, in the most common type...
Hungry gut’ gene test shows who will benefit most from Wegovy – genetics
by Robin Foster You’ve watched others shed pounds in a matter of weeks after taking one of the new blockbuster weight-loss drugs, so you decide to try one of the medications yourself, only to discover the needle on your bathroom scale barely budges. Why? New research presented Monday at the Digestive Disease Week conference in...
Researchers identify mutation that alters Alzheimer’s disease progression
by University of Malaga Researchers identify a mutation that alters Alzheimer’s disease progression. The UMA coordinates this study, carried out by 100 multidisciplinary researchers from 50 different entities. Credit: University of MalagaThe scientist of the Faculty of Medicine of the University of Malaga José Luis Royo has coordinated a study that summarizes eight years of...
Blood mutations increase risk for acute kidney injury, says study
by Vanderbilt University Medical Center Tet2-deficient macrophages are hyperinflammatory in early ischemic kidney injury. Credit: Nature Medicine (2024). DOI: 10.1038/s41591-024-02854-6A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury (AKI), which occurs in more than 1 in 5 hospitalized...