Understanding how this coupled mechanism could lead to new treatments for cancer and other epigenetic diseases. the University of Hong Kong Credit: iStock. A research team led by Professor Yuanliang ZHAI at the School of Biological Sciences, The University of Hong Kong (HKU) collaborating with Professor Ning GAO and Professor Qing LI from Peking University...
A genetic “switch” has been identified that plays a role in controlling anxiety levels, which could provide a new anxiety drug target. University of Aberdeen Credit: Liza Summer/ Pexels New research from the University of Aberdeen has identified an area of DNA in the human genome that plays a role in controlling anxiety. In the...
A newly discovered genetic arrangement may help a common bacterium in the human gut protect itself from a widely used antibiotic. Original story from The Marine Biological Laboratory Credit: Don Stalons/ CDC Antibiotic resistance is a significant and growing medical problem worldwide. Researchers at the Marine Biological Laboratory (MBL) and collaborators have found a novel...
by Vanderbilt University Medical Center Tet2-deficient macrophages are hyperinflammatory in early ischemic kidney injury. Credit: Nature Medicine (2024). DOI: 10.1038/s41591-024-02854-6A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury (AKI), which occurs in more than 1 in 5 hospitalized adults...
by Levi Gadye, University of California, San Francisco Intrinsic reactivity and stability of G12Di-6 and 7. a, Stability in the presence of excess compounds (5 mM) bearing reactive functional groups. All data points represent individual biological replicates. Data are presented as mean ± SD (n = 2). b, Stability in 1X PBS at various pH. All data points represent individual biological...
Peer-Reviewed Publication UMEA UNIVERSITY FATIMA PEDROSA DOMELLÖF, PROFESSOR AT DEPARTMENT OF CLINICAL SCIENCES, UMEÅ UNIVERSITY, SWEDEN.CREDIT: MATTIAS PETTERSSON A specific gene may play a key role in new treatments that prevent muscle in the body from breaking down in serious muscle diseases, muscular dystrophies. This is shown in a new study at Umeå University, Sweden....
by Jeni Bushman, University of Illinois at Urbana-Champaign Summary of the effects from activation of mGluR7 on molecular and behavioral deficits in Fmr1 KO mice. Credit: EMBO Molecular Medicine (2024). DOI: 10.1038/s44321-024-00038-wFragile X syndrome is one of the most commonly inherited forms of autism and intellectual disability, and no treatment currently exists. But a team of...
by University of California – San Diego Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.113867Individuals with the neurodevelopmental disorder Williams syndrome have a gregarious “cocktail party” personality, while those with the opposite genetic alteration, in contrast, tend to have autistic traits and are prone to struggle socially. Now, thanks to new findings by researchers at the Sanford Stem...
by QIMR Berghofer Credit: Unsplash/CC0 Public DomainAn international research team led by QIMR Berghofer and Peter MacCallum Cancer Center has discovered that people with the hereditary cancer disorder Li Fraumeni syndrome are at greater risk of a much broader spectrum of cancers than previously thought. Li Fraumeni syndrome is a rare but devastating condition, which...
by The Hospital for Sick Children Functional characteristics of rare tandem repeat expansions. a Burden of rare tandem repeat expansions in different genomic features in individuals with CMP compared to controls. Credit: eBioMedicine (2024). DOI: 10.1016/j.ebiom.2024.105027In the first study to use whole genome sequencing to examine tandem repeat expansions in heart conditions, scientists at The Hospital...
