Category: <span>Inflammation</span>

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Coffee with milk may have an anti-inflammatory effect

UNIVERSITY OF COPENHAGEN – FACULTY OF SCIENCE Can something as simple as a cup of coffee with milk have an anti-inflammatory effect in humans? Apparently so, according to a new study from the University of Copenhagen. A combination of proteins and antioxidants doubles the anti-inflammatory properties in immune cells. The researchers hope to be able...

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VEXAS Syndrome: More Common, Variable, and Severe Than Expected

Randy Dotinga January 25, 2023 A recently discovered inflammatory disease known as VEXAS syndrome is more common, variable, and dangerous than previously understood, according to results of a retrospective observational study of a large health care system database. The findings, published in JAMA, found that it struck 1 in 4,269 men over the age of 50 in a...

Discovery of pancreatitis treatment target offers new hope
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Discovery of pancreatitis treatment target offers new hope

by Hudson Institute of Medical Research Dr Mohamed Saad. Credit: Hudson Institute of Medical Research It’s a disease in search of a remedy, but Hudson Institute researchers have identified a new pancreatitis treatment target, giving hope to sufferers worldwide. Pancreatitis is a serious inflammatory gastrointestinal disorder which can lead to severe conditions, with as many as 20% of patients...

Vagus nerve receptors may be key to controlling inflammation
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Vagus nerve receptors may be key to controlling inflammation

HEALTH 18 January 2023 By Grace Wade Conditions such as arthritis could be treated by targeting receptors in the vagus nerve that control inflammation Kobus Louw/Getty Images Specific receptors in the vagus nerve help detect and control inflammation in mice. If the same is true for humans, these receptors could be the target of future therapies for...

Alterations in mitochondrial dynamics cause inflammation and muscular atrophy
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Alterations in mitochondrial dynamics cause inflammation and muscular atrophy

INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA) IMAGE: MITOCHONDRIA (IN BLUE), ENDOSOMES (IN WHITE) AND MITOCHONDRIAL DNA (IN ORANGE) FROM A HEALTHY MUSCLE CELL CREDIT: IRB BARCELONA Fragmentation and elongation of mitochondria lead to the activation of inflammatory processes in muscle cells, which result in the development of muscle atrophy, and a diminished resistance to...

Endogenous molecule protects from life-threatening complications after stem-cell transplantation
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Endogenous molecule protects from life-threatening complications after stem-cell transplantation

by Rimma Gerenstein, Albert-Ludwigs-Universität Freiburg im Breisgau  Orally administered hBD-2 is detectable in organs of hBD-2-treated aGVHD mice. The allo-HCT major mismatch model C57BL/6→BALB/c was used. Mice were treated once daily with hBD-2 (n=5) or PBS (n=3) from day 0 until day 7. hBD-2 concentrations in organs were quantified by LC-MS/MS. Credit: Science Translational Medicine (2022). DOI:...

Researchers identify new therapeutic approach to prevent ARDS
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Researchers identify new therapeutic approach to prevent ARDS

by University of California, Irvine Credit: iScience (2022). DOI: 10.1016/j.isci.2022.105901 A novel peptide designed by University of California, Irvine researchers has been found to suppress the damaging lung inflammation seen in acute respiratory distress syndrome, or ARDS. The study, which appears in iScience, describes the first specific treatment designed to prevent the deadly disease, which can appear in patients with...

New kind of eczema cream works by silencing inflammatory genes
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New kind of eczema cream works by silencing inflammatory genes

By Rich Haridy January 12, 2023 A topical cream for dermatitis is just one proposed use for an experimental anti-inflammatory agent Depositphotos A clinical trial is underway testing a new kind of eczema treatment, developed to silence certain genes that play a role in skin inflammation. The results of a preclinical study were recently published...

Excessive scarring shown to be associated with atopic eczema, hypertension and musculoskeletal diseases
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Excessive scarring shown to be associated with atopic eczema, hypertension and musculoskeletal diseases

by King’s College London Keloid formed after operation. One year since surgery. Credit: Michael Rodger/Wikimedia Commons, CC BY Seeking to discover the association between excessive scarring and other conditions, researchers in the School of Immunology & Microbial Sciences and St John’s Institute of Dermatology at King’s College London used medical records available through the UK Biobank to investigate co-morbidities...

Mouse model shows obesity in early life promotes later inflammatory disease, even after weight loss
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Mouse model shows obesity in early life promotes later inflammatory disease, even after weight loss

by Bob Yirka, Medical Xpress Credit: CC0 Public Domain A team of researchers affiliated with multiple institutions in Canada has found that obesity in young mice can lead to inflammatory disease later in life even if the mouse is no longer overweight. In their paper published in the journal Science, the group describes studying early life obesity in...