by Wiley Credit: CC0 Public Domain New research published in Clinical & Experimental Allergy suggests that individuals with inflammatory skin conditions should avoid using skincare products that contain food products such as goat’s milk. The study reports on seven patients with inflammatory skin conditions who experienced anaphylaxis—a serious allergic reaction—after ingesting goat’s or sheep’s milk or cheese products. All...
by Children’s Hospital Boston SARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIH A study led by researchers at Boston Children’s Hospital explains for the first time why COVID-19 causes severe inflammation in some people, leading to acute respiratory distress and multi-organ damage. Surprisingly, the study also...
OSAKA CITY UNIVERSITY IMAGE: MB, NGB, AND CYGB, BUT NOT HB, WERE ENDOCYTOSED INTO THE HSCS VIA ENDOCYTOSIS PATHWAY, SCAVENGED INTRACELLULAR ROS, AND SUPPRESSED COL1A1 PROMOTER ACTIVITY, RESULTING IN HSC DEACTIVATION AND INHIBITION OF COLLAGEN PRODUCTION IN VITRO AND IN VIVO. GLOBIN THERAPY COULD BE UTILIZED AS ANTI-FIBROTIC THERAPY IN HUMAN LIVER CIRRHOSIS. CREDIT: OSAKA...
ANN & ROBERT H. LURIE CHILDREN’S HOSPITAL OF CHICAGO The lower airways of patients with cystic fibrosis (CF) have unique biochemical features that correlate with the complex communities of lung bacteria typical of this disease, according to a multicenter study led by researchers from Ann & Robert H. Lurie Children’s Hospital of Chicago. These findings...
by Kathy Keatley Garvey, UC Davis A control burn at the University of California, Davis. Credit: Kathy Keatley Garvey Every year some 10,000 burn victims in the United States undergo an acute inflammatory reaction and die of burn-related infections, according to the Centers for Disease Control and Prevention. Now a newly published study by a...
by Weill Cornell Medical College Opportunistic ‘high-damaging’ Candida albicans strain in the colon mucosa of IBD patient secretes the toxin candidalysin (red dots) during the transition from a benign commensal to a pathogenic state and aggravates intestinal inflammation. Credit: Shutterstock Individual Candida albicans yeast strains in the human gut are as different from each other...
Yi Zhou, BA1; James Murrough, MD, PhD2; Yinxi Yu, MS3; et alNeeta Roy, PhD4; Rony Sayegh, MD5; Penny Asbell, MD4; Maureen G. Maguire, PhD3; Gui-shuang Ying, PhD1; for the DREAM Study Research GroupAuthor AffiliationsArticle Information JAMA Ophthalmol. Published online March 10, 2022. doi:10.1001/jamaophthalmol.2022.0140editorial comment icon Editorial Comment Key Points Question Is severity of dry eye symptoms and signs associated with presence of depression? Findings In this multicenter study of 535 participants with dry eye disease, those who screened positive for...
The findings provide promise of targeted treatment for patients with the disease. Investigators have discovered that a biodegradable nanoparticle used in medical sutures could combat a rare, sometimes-fatal autoimmune disease. Researchers found that a unique macrophage, an immune cell that removes bacteria or dead cells, plays a key role in the chronic inflammation and scarring...
by Dr Sophia Davidson, University of Melbourne Credit: CC0 Public Domain “How many people actually have this disease?” It’s a potentially triggering question at a family BBQ. I had just finished explaining why I’d recently traveled to the U.S. to work on samples from patients with a rare disease called proteasome related autoinflammatory syndrome (PRAAS)....
by Monash University Credit: Pixabay/CC0 Public Domain A recent study by Monash University has found that proteins found naturally in tick saliva, called evasins, can be modified to block the activity of important proteins in human inflammatory diseases such as arthritis, asthma and multiple sclerosis. The study, conducted at the Monash Biomedicine Discovery Institute, showed...
