by Karolinska Institutet Gastrointestinal System. Credit: Blausen.com staff (2014). “Medical gallery of Blausen Medical 2014”. WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. CC BY 3.0 Inflammatory bowel disease (IBD), with its two main disease entities Crohn’s disease and ulcerative colitis, is a chronic and relapsing inflammation of the gastrointestinal tract. The highest prevalence of...
by Melissa Rohman, Northwestern University Muller’s lab recently demonstrated that calcium flux in endothelial cells is tightly coupled temporally and spatially with leukocyte transmigration. The arrows depict local elevation of [Ca2+]i (green) at endothelial junctions (blue) as neutrophils (red) transmigrate across a postcapillary venule in the mouse cremaster muscle in response to the inflammatory cytokine,...
JANUARY 14, 2022 by Ludwig Maximilian University of Munich Immunofluorescence image of lung tissue showing co-localization of TRPML3 (green) and macrophages (red). Credit: Barbara Spix Chronic obstructive pulmonary disease—COPD for short—is one of the most common diseases of the lung. It affects almost 300 million people worldwide, of which about three million die every year. A...
JANUARY 17, 2022 by RCSI University of Medicine and Health Sciences Figure 1. 2D validation of ECM substrate combinations and ratios. A) Significant changes in proliferation via dsDNA content in S42 Schwann cells at day 7 using a variety of ECM coatings compared to plates coated with 50 µg/ml of collagen I only B) No...
UNIVERSITY OF CALIFORNIA – LOS ANGELES HEALTH SCIENCES IMAGE: SCIENTISTS DERIVED THE CONCENTRATE, WHICH CONTAINS ANTI-INFLAMMATORY AND ANTIOXIDANT PROPERTIES, FROM GENETICALLY MODIFIED TOMATOES. CREDIT: ARINA KRASNIKOVA/PEXELS New UCLA-led research in mice suggests that adding a certain type of tomato concentrate to the diet can reduce the intestinal inflammation that is associated with HIV. Left untreated,...
by Melissa Rohman, Northwestern University Immunostaining of protein constituents of the cell-cell adhesive junction in the desmosome in skin biopsies taken from a patient with SAM syndrome harboring a genetic mutation in Dsg1. The levels of Dsg1 and its associated partner protein plakoglobin (PG) are restored at cell borders following ustekinumab treatment. Credit: Northwestern University...
by British Medical Journal Credit: Pixabay/CC0 Public Domain Living alone for several years and/or experiencing serial relationship break-ups are strongly linked to raised levels of inflammatory markers in the blood–but only in men–finds a large population study published online in the Journal of Epidemiology & Community Health. Although the inflammation was classified as low grade, it...
by George Washington University Nearly 2 million new cases of pediatric asthma every year may be caused by a traffic-related air pollutant, according to a new study published today. Credit: Chris Leboutillier Nearly 2 million new cases of pediatric asthma every year may be caused by a traffic-related air pollutant, a problem particularly important in...
by Kaylee Dusang, Baylor College of Medicine Credit: Pixabay/CC0 Public Domain Although allergies are normally associated with the spring and fall, it may feel like allergy season never left this winter. From cold fronts to rainy days and back to warmer days, an allergy expert at Baylor College of Medicine explains that it is not...
by Monash University Credit: CC0 Public Domain A cell therapy could reduce inflammatory response in liver disease, offering hope to thousands of Australians suffering from the disease. Inflammation underpins hundreds of health conditions, contributing to more than 50 percent of deaths worldwide, and Hudson Institute has Australia’s largest team of inflammation researchers, whose sole focus is...
