by Indiana University Credit: Unsplash/CC0 Public Domain Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified how restoring a missing molecule in pancreatic fibrosis could help deliver treatments to cancer cells. Pancreatic cancer is one of the deadliest cancers with only 10.8 percent of people surviving five years after diagnosis. One risk factor for...
(HealthDay)—The use of patient-reported outcome measures (PROMs) to complement clinician-reported outcomes (CROs) may yield important information for assessing disease severity and guiding treatment of psoriasis, according to a research letter published online Sept. 8 in JAMA Dermatology. John S. Barbieri, M.D., and Joel M. Gelfand, M.D., both from the University of Pennsylvania Perelman School of Medicine...
by University of Oslo Professor Farrukh Abbas Chaudhry (at the back) and his research group has taken an important first step towards finding a cure for liver encephalopathy, or at the very least a treatment for its symptoms. Up front lead author El Hassan Hamdani, who is now working at OsloMet, in the middle Marivi Moen. Credit: El Hassan Hamdani Liver encephalopathy is one...
by University of Chicago Medical Center Credit: Unsplash/CC0 Public Domain A study led by researchers at the University of Chicago and Indiana University has determined that a protein called elF5A is necessary for driving inflammation in macrophage cells in obesity. Blocking DHPS, the enzyme that modifies and activates elF5A, led to reduced inflammation and improved glucose control in...
UNIVERSITY OF CHICAGO MEDICAL CENTER A study led by researchers at the University of Chicago and Indiana University has determined that a protein called elF5A is necessary for driving inflammation in macrophage cells in obesity. Blocking DHPS, the enzyme that modifies and activates elF5A, led to reduced inflammation and improved glucose control in mice. The study was...
by Brigham and Women’s Hospital Credit: Pixabay/CC0 Public Domain For hundreds of years, people have observed that asthma severity often worsens in the nighttime. One longstanding question has been to what degree the body’s internal circadian clock—as opposed to behaviors, such as sleep and physical activities—contributes to worsening of asthma severity. Using two circadian protocols, investigators...
Patients with chronic rhinosinusitis sometimes suffer from the growth of polyps in the nasal cavity. These polyps are difficult to treat and often require surgical intervention. Even after removal by surgery, polyps can return and present a significant health burden for patients. White blood cells are known to release inflammatory signals that stimulate polyp growth....
by University of Michigan Credit: Unsplash/CC0 Public Domain Results from a Michigan Medicine study reveal that targeting a protein found in the skin may reduce the severity of psoriasis. Interferons play a major role in activating the body’s response to viral threats, but they have also been detected in the lesions of many psoriasis patients at...
by Marcene Robinson, University at Buffalo Praveen Arany, assistant professor of oral biology in the UB School of Dental Medicine, led the development of a burn healing protocol for light therapy. Credit: Douglas Levere Light therapy may accelerate the healing of burns, according to a University at Buffalo-led study. The research, published in Scientific Reports, found that photobiomodulation...
WILEY In a study of 1,377 patients with rheumatic and musculoskeletal diseases—such as inflammatory arthritis and lupus—flares of their conditions were uncommon following two-dose COVID-19 mRNA vaccination. In a study of 1,377 patients with rheumatic and musculoskeletal diseases—such as inflammatory arthritis and lupus—flares of their conditions were uncommon following two-dose COVID-19 mRNA vaccination. In the Arthritis...
