During a 1989 lecture at the Cold Spring Harbor Symposium on Quantitative Biology, Yale School of Medicine professor Charles Janeway, MD, hypothesized the existence of an innate immune system and special receptors on immune cells (currently known as toll-like receptors) that trigger the body’s response to infection. Janeway’s research later confirmed his insights, providing the...
Category: <span>Inflammation</span>
Treating skin irritations from wearing face masks
by From Mayo Clinic News Network, Mayo Clinic News Network Since many people are wearing face masks because of COVID-19 pandemic requirements, skin irritations on the face might be more prevalent. “People are getting friction and irritation across their nasal bridge, behind their ears and perhaps under their chin,” says Dr. Dawn Davis, a Mayo...
COVID-19 cytokine storm: Possible mechanism for the deadly respiratory syndrome
by Hokkaido University Research into how the SARS-CoV-2 virus induces death is suggesting potential treatments for its most destructive complications. Leading immunologists in Japan are proposing a possible molecular mechanism that causes massive release of proinflammatory cytokines, or a cytokine storm, leading to the acute respiratory distress syndrome (ARDS) in COVID-19 patients. Their suggestions, published...
Adding a blend of spices to a meal may help lower inflammation
UNIVERSITY PARK, Pa. — Adding an array of spices to your meal is a surefire way to make it more tasty, but new Penn State research suggests it may increase its health benefits, as well. In a randomized, controlled feeding study, the researchers found that when participants ate a meal high in fat and carbohydrates...
Uncovering how ‘dark matter’ regions of the genome affect inflammatory diseases
by Babraham Institute A study led by researchers at the Babraham Institute in collaboration with the Wellcome Sanger Institute has uncovered how variations in a non-protein coding ‘dark matter’ region of the genome could make patients susceptible to complex autoimmune and allergic diseases such as inflammatory bowel disease. The study in mice and human cells...
From Depression to Dementia, Inflammation Is Medicine’s New Frontier
he barrier between mind and body appears to be crumbling. Clinical practice and public perception need to catch up. The GuardianEdward Bullmore Unlikely as it may seem, #inflammation has become a hashtag. It seems to be everywhere suddenly, up to all sorts of tricks. Rather than simply being on our side, fighting infections and healing...
Enzyme could hold key to improved allergy treatments
A class of immune cells push themselves into an inflammatory state by producing large quantities of a serotonin-making enzyme, according to a study in mice led by scientists at Weill Cornell Medicine. The study, published in Immunity, found that the inflammatory and infection-fighting abilities of the cells, called type 2 innate lymphoid cells (ILC2s), are...
Temple finds link between blood vessel inflammation, malfunctioning cellular powerhouses
CREDIT: TEMPLE UNIVERSITY HEALTH SYSTEM (Philadelphia, PA) – The vast majority of cells in the human body contain tiny power plants known as mitochondria that generate much of the energy cells use for day-to-day activities. Like a dynamic renewable resource, these little power plants are constantly dividing and uniting in processes called fission and fusion....
Researchers discover key mechanism of cytokine storm in Castleman disease
by Perelman School of Medicine at the University of Pennsylvania When Castleman Disease patients have a flare of their symptoms, they experience a cytokine storm inside their bodies—a hyper-response from the immune system that can cause a fever, organ failure, and even death. Now researchers at the Perelman School of Medicine at the University of...
NHS issues urgent alert amid spike in the number of children being admitted to intensive care with a new coronavirus-related ‘inflammatory syndrome’
By SAM BLANCHARD SENIOR HEALTH REPORTER FOR MAILONLINE and STEPHEN MATTHEWS HEALTH EDITOR FOR MAILONLINE he illness is similar to COVID-19, doctors say, but some children test negative Children with the condition have been found to have swelling in their hearts Young people have been largely unaffected during the coronavirus pandemic Here’s how to help...