UNIVERSITY OF BRITISH COLUMBIA A new study suggests that specialized immune cells that dampen inflammation and help repair the gut could be used as a potential therapy for children dealing with the painful symptoms of inflammatory bowel disease (IBD). The research from BC Children’s Hospital and the University of British Columbia shows that a specific...
Category: <span>Inflammation</span>
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Researchers develop approach to alter intestinal microbiota, vaccinate against inflammatory diseases
GEORGIA STATE UNIVERSITY ATLANTA–Targeted immunization against bacterial flagellin, a protein that forms the appendage that enables bacterial mobility, can beneficially alter the intestinal microbiota, decreasing the bacteria’s ability to cause inflammation and thus protecting against an array of chronic inflammatory diseases, according to a new study by the Institute for Biomedical Sciences and the Neuroscience...
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Dead probiotic strain shown to reduce harmful, aging-related inflammation
by Wake Forest University Baptist Medical Center Scientists at Wake Forest School of Medicine have identified a dead probiotic that reduces age-related leaky gut in older mice. The study is published in the journal GeroScience. But what exactly is leaky gut and what does a probiotic—dead or alive—have to do with it? Some research has...
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Inhibiting a protease could improve the treatment of inflammatory bowel disease
The study, published in EMBO Molecular Medicine, shows that blockade of the protease MT1-MMP protects the vasculature in the inflamed gut CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.) Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Centro de Investigaciones Biológicas (CIB) of the Consejo Superior de Investigaciones Científicas (CSIC) have identified...
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Trinity researchers uncover critical metabolic switch for inflammatory diseases
A research team in Trinity has uncovered a critical role for a protein called ‘PKM2’ in the regulation of immune cell types at the heart of multiple inflammatory diseases. The work identifies PKM2 as a potential therapeutic target for treating a host of diseases mediated by over-active immune cells, such as psoriasis and multiple sclerosis. Credit: Trinity...
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New insights into how immune system and inflammation play a role in PD
Reviewed by Kate Anderton, B.Sc. (Editor) Relatively new research findings indicating that the earliest stages of Parkinson’s disease (PD) may occur in the gut have been gaining traction in recent years. In a review published in the Journal of Parkinson’s Disease, Tomasz Brudek, PhD, evaluates evidence for the association between inflammatory bowel disease (IBD) and...
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Link between inflammation and mental sluggishness shown in new study
by Beck Lockwood, University of Birmingham Scientists at the University of Birmingham in collaboration with the University of Amsterdam have uncovered a possible explanation for the mental sluggishness that often accompanies illness. An estimated 12 million U.K. citizens have a chronic medical condition, and many of them report severe mental fatigue that they characterize as...
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Revealed a mechanism of beta-cells involved in the development of type-1 diabetes
Researchers reveal how pancreatic ß-cells respond to an inflammatory environment and its implication in developing Type 1 diabetes JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE Researchers Lorenzo Pasquali and Mireia Ramos-Rodríguez have published recently in Nature Genetics the results of a study on the mechanisms that cause an inflammatory response to trigger pancreatic beta-cell death, leading to...
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Why beta-blockers cause skin inflammation
University study finds possible cause of a known phenomenon UNIVERSITY OF BONN Beta-blockers are often used to treat high blood pressure and other cardiovascular diseases. However, in some patients they can trigger or exacerbate psoriasis, an inflammatory skin disease. Scientists at the University of Bonn and Freie Universität Berlin have now found a possible cause...
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Study: Chronic inflammatory effect in the oral cavity from alcohol, tobacco and caffeine
by Asociacion RUVID Researchers of the CEU UCH university have published the first pilot study on the alterations to the levels of cytokines in the saliva of frequent consumers of these three stimulating substances Cytokines are proteins released by the cells of the immune system to regulate the mechanism of inflammation against infections. When cytokine...