Research team discovers alternate pathway by which MSU crystals trigger inflammation WASHINGTON STATE UNIVERSITY SPOKANE, Wash. – Researchers at Washington State University Health Sciences Spokane and elsewhere have identified a new therapeutic target for the treatment of gout, a common type of arthritis that causes episodes of painful and stiff joints. Published in the journal...
Category: <span>Inflammation</span>
Post
New research divided over links between inflammation and depression
By Rich Haridy Over the last decade an idea that once sat on the fringes of mainstream science has slowly edged its way closer to the center. Since the 1980s researchers have identified a distinct association between inflammation and depression. Of course, alongside that research the biggest development in the field of psychiatry in the...
Post
Hope offered to patients with a rare autoimmune condition
NEWCASTLE UNIVERSITY A new study has shed light on a debilitating autoimmune condition by identifying a number of sub types of the disease which could lead to personalized treatment for patients. For the first time, scientists at Newcastle University, UK, have found there are at least four versions of primary Sjögren’s syndrome (PSS) – a...
Post
Arthritis treatment could provide relief for lichen planus skin rash
by Haley Otman, University of Michigan It’s often difficult to manage patients with this skin inflammation, but new research identifies a target that existing medications are able to address. Constant itchy, painful bumps, scaly arms and legs, and damaged nails make lichen planus an inflammatory skin disease that’s both frustrating and painful for patients trying to keep their quality of life. The...
Post
Inflammation amps up neurite growth, gene expression involved in heat, cold sensitivity
by Tracey Peake, North Carolina State University Researchers from North Carolina State University have found that inflammation increases neuronal activity, gene expression and sensory nerve (neurite) outgrowth in neurons involved in thermal—but not physical- sensations in mice. The work sheds light on the role that inflammation-induced over expression of calcium channel genes may play in...
Post
Research suggests new approach for treating inflammation
by Emil Venere, Purdue University Medications that mitigate inflammation caused by a variety of diseases including rheumatic arthritis may also compromise a person’s immune system, but a new approach points to a possible solution to this problem. Researchers have discovered a mechanism that might alleviate inflammation by suppressing the migration of a type of white...
Post
Inflammation triggers silent mutation to cause deadly lung disease
Date:August 29, 2019 Source:Stanford Medicine Summary:Researchers have found that inflammation in the lungs of rats, triggered by something as simple as the flu, may wake up a silent genetic defect that causes sudden onset cases of pulmonary hypertension, a deadly form of high blood pressure in the lungs. Researchers at the Stanford University School of...
Post
Treating inflammation with inflammation
by Ana Gajic, St. Michael’s Hospital Scientists at the Keenan Research Centre for Biomedical Science (KRCBS) have uncovered a new potential approach to treat multiple types of autoimmune disease including arthritis in lab models. Two million Canadians live with autoimmune diseases, which are conditions such as arthritis or lupus that cause a body’s immune system...
Post
Brain Inflammation in Patients with Fibromyalgia
By Osman Shabir, M.Sc. Reviewed by Dr. Jennifer Logan, MD, MPH Fibromyalgia is a condition in which there is extensive chronic pain across the body with an increased pain response to pressure, which would normally not be painful. Central to the pathogenesis of fibromyalgia is impaired nociceptive (pain) signal processing in the nervous system. Therefore, fibromyalgia in its pure form is...
Post
Using a common anticonvulsant to counteract inflammation
by Tokyo University of Science Serious conditions, including sepsis, stem from inflammation in the body, and there is a lack of effective medication for sepsis. A chromosomal protein called high-mobility group box 1 (HMGB1), secreted by immune and dying cells, binds to a specific cellular receptor—receptor for advanced glycation end-products (RAGE)—and triggers the process of inflammation in the body. Through...