by University of Cambridge Credit: Pixabay/CC0 Public DomainSARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression. New research shows that in long COVID patients, IFN-y production persists until symptoms improve, highlighting a potential biomarker and a target for therapies. A University of Cambridge-led study identifies the protein...
by NDORMS, University of Oxford Tissue sections show frozen shoulder patient tissues exhibit an increased number of cells and blood vessels relative to non-diseased comparator shoulder capsule. Credit: Prof. Stephanie DakinResearchers have identified how cells work to resolve frozen shoulder, opening up potential new targets for treatment and reducing the need for surgery. Frozen shoulder is...
by Salk Institute Endosomes (magenta) collect around mitochondria (blue) after infection with virus HSV-1, which attacks mtDNA (green) and causes its release. Credit: Salk InstituteCells in the human body contain power-generating mitochondria, each with their own mtDNA—a unique set of genetic instructions entirely separate from the cell’s nuclear DNA that mitochondria use to create life-giving energy....
by European Alliance of Associations for Rheumatology (EULAR) Credit: Unsplash/CC0 Public DomainHemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) are life-threatening systemic hyperinflammatory syndromes. Systemic hyperinflammation and HLH/MAS can occur in nearly any inflammatory state, but there are certain predisposing conditions and inflammatory triggers. This includes rheumatic diseases, malignancies, metabolic diseases, and genetic immune problems....
by University of Cambridge Graphical abstract. Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.113700Cambridge scientists may have discovered a new way that fasting helps reduce inflammation, a potentially damaging side-effect of the body’s immune system that underlies a number of chronic diseases. In a paper titled “Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain...
Peer-Reviewed Publication UNIVERSITY OF CAMBRIDGE Cambridge scientists may have discovered a new way in which fasting helps reduce inflammation – a potentially damaging side-effect of the body’s immune system that underlies a number of chronic diseases. In research published in Cell Reports, the team describes how fasting raises levels of a chemical in the blood...
by Lori Solomon Some patients seen in an inflammatory bowel disease (IBD) clinic screen positive for malnutrition, according to a research letter published online Nov. 20 in Gastro Hep Advances. Aaron C. Viser, from the University of North Carolina at Chapel Hill, and colleagues used data from a multidisciplinary IBD clinic (June 7 to July...
Jan 10 2024Medical University of ViennaAs the cause of chronic inflammatory bowel diseases (IBD) such as Crohn’s disease or ulcerative colitis is not yet known, treatment for sufferers is currently aimed at alleviating the often agonizing symptoms. The discovery by a MedUni Vienna research team that the trigger for IBD could be found on the...
Study suggests stress management could reduce biological riskPeer-Reviewed Publication OHIO STATE UNIVERSITY COLUMBUS, Ohio – Lifestyle and genetics, and a range of other factors within and outside our control, are known to contribute to development of metabolic syndrome, a cluster of conditions that add up to increased risk for serious health problems. A new study...
by Tulane University Transmission electron micrograph of RSV. Credit: CDC/ Dr. Erskine Palmer / Public DomainRespiratory syncytial virus (RSV), a common infection in children and senior adults, can also infect nerve cells and trigger inflammation leading to nerve damage, according to a new Tulane University study. RSV can cause mild symptoms such as coughing, sneezing and...
