Peer-Reviewed Publication BAYLOR COLLEGE OF MEDICINE Inflammation is a risk factor for many chronic diseases, including cardiovascular disease (CVD), and the impact of diet on inflammation is an area of growing scientific interest. In particular, recommendations to limit red meat consumption are often based, in part, on old studies suggesting that red meat negatively affects...
Category: <span>Inflammation</span>
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Almost half of patients with skin disease suffer from sleep disturbances, global study finds
by European Academy of Dermatology and Venereology Credit: Unsplash/CC0 Public DomainAlmost half (42%) of patients with skin disease experience sleep disturbances, a major study presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2023 has revealed. The ALL PROJECT, a comprehensive international research initiative, analyzed over 50,000 adults across 20 countries to...
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Intestinal ultrasound monitoring cuts time to treatment change in inflammatory bowel disease
by Elana Gotkine For patients with inflammatory bowel disease (IBD), monitoring by intestinal ultrasound (IUS) results in reduced time to treatment change and to remission, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 20 to 25 in Vancouver, British Columbia, Canada. Noa Krugliak Cleveland, M.D.,...
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Newly discovered compound blocks signaling pathway of immune response
by CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences SLC15A4-TASL binding interface and drug screening for TASL stability. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-42070-3Scientists at CeMM, the Medical University of Vienna, and the University of Lausanne have succeeded for the first time in identifying and characterizing a new small molecule called...
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COVID Coronary Plaque Infection Confirms CV Risk
Sue Hughes and Allison Shelley October 23, 2023 New evidence shows for the first time that the virus that causes COVID directly infects atherosclerotic plaques in the coronary arteries, producing a persistent inflammatory response. The findings may not only explain the link between COVID and the increased risk of cardiovascular events but mark a starting point for...
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Brain clues in the battle against long COVID: study pinpoints neuroinflammation
Dr. Priyom Bose, Ph.D.By Dr. Priyom Bose, Ph.D.Oct 25 2023Reviewed by Lily Ramsey, LLMThe coronavirus disease 2019 (COVID-19) pandemic has led to a public health crisis known as long-COVID, or post-acute sequelae of COVID-19 (PASC). A recent study published on the bioRxiv* preprint server analyzed the relationship between circulating markers of vascular dysfunction and neuroinflammation...
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B12 deficiency: A hidden trigger of inflammation?
by Society of Chemical Industry Binned scatterplot of the relationship between vitamin B12 and IL-6 (A) and CRP (B) in humans adjusted for sex, age, education level, smoking habit, BMI, physical activity, diabetes, hypertension, hypercholesterolemia, aspirin, medication, energy intake, alcohol consumption and Mediterranean diet adherence. IL-6, interleukin-6. CRP, C-reactive protein. Credit: Journal of the Science...
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Knee pain? Genicular artery embolization can offer relief
by Merve Ozen, University of Kentucky Credit: Pixabay/CC0 Public DomainOf all the joints in the body, the knees get the most wear and tear. Decades of walking, running, sitting, jumping and other activities can take a toll on the cartilage—the smooth tissue between the bones—leading to osteoarthritis. The resulting pain and stiffness can limit mobility...
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Study shows timing is key in cortisone treatment of inflammation
by Ute Schönfelder, Friedrich-Schiller-Universität Jena Dexamethasone (Dex) impacts LM biosynthetic pathways during M1 and M2 polarization in a concentration-dependent manner. (A, B, C) Human monocytes-derived macrophages (MDM, 2 × 106 cells/ml) were preincubated with Dex at different concentrations as indicated (Dex, blue) or vehicle (0.1% DMSO, black) for 15 min and were then polarized for...
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Novel biologic Ab-IPL-IL-17 shows promise for rheumatoid arthritis and inflammatory bowel disease
by University of Birmingham Credit: Pixabay/CC0 Public Domain Researchers have shown that a novel antibody generated to target an ‘essential amino acid sequence’ of both interleukin-17A and F has greater activity and potentially fewer side effects than existing biological therapies for conditions such as as rheumatoid arthritis (RA), psoriasis, and inflammatory bowel disease (IBD). The antibody, called...