by Allessandra DiCorato, Broad Institute of MIT and Harvard Credit: Sonja Vasiljeva, Broad Communications Our bodies burn carbohydrates, proteins, and fat for fuel, and now, researchers at the Broad Institute of MIT and Harvard and the University of Lausanne have discovered another important energy source for cells: uridine, the chemical building block unique to RNA. Their new findings...
by Serena Crawford, Yale University Uyen To, MD. Credit: Yale University Uyen To, MD, assistant professor of medicine (digestive diseases) and transplant hepatologist, discusses how she first became interested in studying Wilson disease, the wide spectrum of symptoms caused by the rare condition, and what’s next in this fascinating field of research. What is Wilson disease? Wilson...
by Maynooth University Credit: CC0 Public Domain Maynooth University’s Kathleen Londsdale Institute for Human Health Research has just published research into the benefits of the popular obesity treatment drug, GLP-1. Previous research has found that people with obesity are at a greater risk of developing cancer, in part due to their anticancer immune cells—better known as the ‘Natural Killer (NK)’ cell—being rendered...
by CU Anschutz Medical Campus Metabolic signatures of short/high-intensity and long/low-intensity training regimens. A During the training camp, whole blood from 28 Elite World Tour cyclists was sampled before and after a 1 h graded exercise test on an ergometer. B Whole blood lactate measurements (millimolar) as a function of normalized power output (W·kg−1) during the test. C During the same training camp,...
HIGHER EDUCATION PRESS IMAGE: TLCL DEFICIENCY REDUCES OXPHOS EFFICIENCY. CREDIT: PATRICK J FERRARA, MARISA J LANG, JORDAN M JOHNSON, SHINYA WATANABE, KELSEY L MCLAUGHLIN, J ALAN MASCHEK, ANTHONY R P VERKERKE, PIYARAT SIRIPOKSUP, AMANDINE CHAIX, JAMES E COX, KELSEY H FISHER-WELLMAN, KATSUHIKO FUNAI Weight regains is a common problem for weight loss individuals. A number...
by Chinese Academy of Sciences Subfornical organ neurons sense PTH level and regulate PTH secretion. Credit: Yang Fan Bones are not stagnant structures. According to recent studies, bones maintain a lively metabolism and closely interact via nerves with the brain. But whether endocrine hormones also play an important role in brain-bone talk has been unclear. Researchers from...
Maintaining weight loss may be influenced by the levels of a particular hormone. Ivan Andrianov/Stocksy Obesity is linked to many health conditions and is associated with the leading causes of death globally. Attempts to lose excess weight through lifestyle changes are often thwarted by the fact that the majority of people who do manage to...
by Stephanie McPherson, Broad Institute of MIT and Harvard Human pancreatic beta cells show increased membrane rigidity (indicated in red) when exposed to erucic acid, a toxic monounsaturated fatty acid. Credit: Ranjan Devkota and Juliana Coraor Fried Researchers have developed a technology, FALCON, to analyze the effects of free fatty acids in any cell type, and found...
by Impact Journals LLC Credit: Unsplash/CC0 Public Domain A new research paper titled “Selenium as a predictor of metabolic syndrome in middle age women” has been published in Aging. Metabolic syndrome (MetS) is a widespread clinical entity that has become almost a global epidemic. Selenium plays an important role in metabolic homeostasis. It has been suggested that it...
by American College of Physicians Credit: Pixabay/CC0 Public Domain An emulated randomized trial performed using observational data from more than 43,000 adults with primary hyperparathyroidism found that parathyroidectomy had no estimated effect on long-term kidney function in older adults when compared to observation. However, early parathyroidectomy may preserve kidney function in patients younger than 60 years...
