by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) Electron microscopy images of lung macrophages in a normal mouse (left) and in a mouse deficient for mitochondrial oxidative phosphorylation (right). mn obtenida por microscopia electrónica de un macrófago pulmonar de un ratón normal (izquierda) y un macrófago con deficiencia en la fosforilación oxidativa mitocondrial (derecha)....
by University of Science and Technology of China The neural pathway for metabolic modulation by light in mice. Credit: Prof. Xue Tian’s team A research team led by Prof. Xue Tian from the University of Science and Technology of China (USTC) revealed the neural mechanism of photoreception suppressing thermogenesis in brown adipose tissue (BAT), thereby reducing glucose...
HEBREW SENIORLIFE HINDA AND ARTHUR MARCUS INSTITUTE FOR AGING RESEARCH BOSTON – A new study published in the Journal of Clinical Endocrinology and Metabolism found that age-related accumulation of abdominal fat is associated with lower muscle density. Low muscle density means the muscle has more fat in it, which can lead to less effective muscle function that...
by The Francis Crick Institute Researchers gathered experimental data to put into the model by measuring the levels of gene expression in liver and liver tumours from mice that had been fed either ‘healthy’ diets or ‘unhealthy’ diets, rich in fats and sugars. Credit: The Francis Crick Institute Researchers at the Francis Crick Institute and King’s College...
by University of Montreal Credit: CC0 Public Domain In a crucial step towards understanding the mechanisms involved in cardiovascular disease and certain cancers, a Canadian led research team has succeeded in a world first: they’ve found the molecular mechanism by which the protein PCSK9 degrades the receptor of low density lipoproteins, the richest cholesterol particles in the...
The find could lead to more effective treatments for childhood obesity and cancer. While the research was in fruit fly larvae, being able to speed up or slow down lipid metabolism could have significant implications for human health, says Hua Bai, an associate professor of genetics, development and cell biology at Iowa State University. “We’ve identified what’s...
by Baylor College of Medicine Credit: Unsplash/CC0 Public Domain Researchers at Baylor College of Medicine have found more evidence that dry fasting (fasting without food or liquid intake) from dawn to dusk can play an important role in overall health. In a new study published in Metabolism Open, researchers found that fasting from dawn to dusk for four...
by Salk Institute Graphical abstract. Credit: Cell Metabolism (2023). DOI: 10.1016/j.cmet.2022.12.004 Obesity and metabolic diseases, such as diabetes, are extremely common in the United States. Tiny proteins called microproteins have long been overlooked in research, but new evidence demonstrates that they have an important role in metabolism. Salk scientists have discovered that both brown and white fat is...
Reviewed by Emily Henderson, B.Sc.,Dec 30 2022 As a chronic pro-inflammatory disease, obesity is closely associated with the development of various diseases such as type 2 diabetes, cardiovascular disease and cancers. Obesity is now a major concern for public health. Macrophages have been known to play an important role in the development of obesity. Recent...
by Wu Tsai Human Performance Alliance Credit: Shutterstock Older women heal bone fractures slower than men. Now a team has found that a single, localized delivery of estrogen to a fracture can speed up healing in postmenopausal mice. The findings could have implications for the way fractures in women are treated in the future. Over...
