Authors: Stephenson, Dianea | Badawy, Rehamb | Mathur, Soaniac | Tome, Mariad | Rochester, Lynne Abstract The burden of Parkinson’s disease (PD) continues to grow at an unsustainable pace particularly given that it now represents the fastest-growing brain disease. Despite seminal discoveries in genetics and pathogenesis, people living with PD oftentimes wait years to obtain an accurate diagnosis and have no way to know...
by Kumamoto University Ar-turmerone has an asymmetric carbon that naturally exists in a structure similar to A (S-Tur). Researchers identified three analogs (B, C, and D) that have stronger anti-inflammatory activity than S-Tur. Credit: Hori, Y. et.al., Cells, 2021, CC by 4.0 Researchers from Kumamoto University, Japan have found that a component derived from turmeric essential oil, aromatic...
New research highlights the importance of dancing to music for halting Parkinson’s disease. Raymond Forbes/Stocksy A study investigated how dancing to music affects various symptoms of Parkinson’s disease. The results suggest that dancing to music can halt the progression of physical and psychological symptoms of Parkinson’s. The researchers say the results could aid in developing...
by Michael Sheffield, St. Jude Children’s Research Hospital From left: Hanwen Zhu, Ph.D.; Ji Sun, Ph.D.; and Patricia Hixson, Ph.D., all of St. Jude Structural Biology, have determined the detailed structure of an enzyme whose mutated forms are known to cause Parkinson’s disease. Credit: St. Jude Children’s Research Hospital Structural biologists at St. Jude Children’s Research Hospital have determined the...
Parkinson’s disease is the second most common neurodegenerative disease and affects more than 10 million people around the world. To better understand the origins of the disease, researchers from Penn State College of Medicine and The Hebrew University of Jerusalem have developed an integrative approach, combining experimental and computational methods, to understand how individual proteins...
by Mrs Amy King, University of Plymouth Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia A new study has shown that anxiety amplifies the physical signs of Parkinson’s disease, according to people who experience both conditions. The study, believed to be the first to...
by Zhang Nannan, Chinese Academy of Sciences Fig.1. Schematic summary of the exacerbated α-syn neuropathology in heterozygous familial PD. Credit: SIOC Amyloid deposition of α-synuclein (α-syn) is a hallmark of Parkinson’s disease (PD). α-Syn fibrillation and cell-to-cell transmission in the brain play an essential role in disease progression. To date, eight single-point mutations of SNCA have...
by Brigham and Women’s Hospital Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia A key driver of patients’ well-being and clinical trials for Parkinson’s disease (PD) is the course the disease takes over time. However, nearly all that is known about the genetics of...
UNIVERSITY OF CALIFORNIA – SAN FRANCISCO Pioneering neural recordings in patients with Parkinson’s disease by UC San Francisco scientists lays the groundwork for personalized brain stimulation to treat Parkinson’s and other neurological disorders. In a study published May 3rd in Nature Biotechnology, UCSF Weill Institute for Neurosciences researchers implanted novel neurostimulation devices that monitor brain activity for many...
By JACK NEWMAN FOR MAILONLINE Scientists have discovered a frontal-temporal disconnection which could explain why people with Parkinson’s believe they can see ghosts. Around half of people suffering with the disease experience ‘presence hallucinations’ which causes them to sense a shadowy presence nearby. The spontaneous nature of the event has made the phenomena hard to study....
